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Anti-UBR2 Antibody (aa1618-1631) IHC-plus™ LS-B9517

Note: This antibody replaces LS-C112884

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular UBR2 Antibodies

Anti-UBR2 Antibody (C-Terminus) LS-C82458
Rabbit Polyclonal (IgG) to Human UBR2
Human, Horse, Rabbit
Western blot
Unconjugated
Western blot Image
Anti-UBR2 Antibody (aa1618-1631) IHC-plus™ LS-B9517
Goat Polyclonal to Human UBR2
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-UBR2 Antibody LS-C332537
Rabbit Polyclonal (IgG) to Human UBR2
Human, Mouse
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human UBR2
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
IHC - Paraffin, ELISA
Unconjugated

Details

Human UBR2
Goat
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • ELISA (1:32000)

Specificity and Use

UBR2 antibody was raised against synthetic peptide SCPKSGGDKSRAPT from an internal region of human UBR2 (NP_056070.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Lizard (100%); Bat, Xenopus (93%); Stickleback, Pufferfish, Zebrafish (86%).
LS-E27184 - Lyophilized - 100 µg - $145.00
aa1618-1631
Human UBR2.
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments gave bands at approx 150kDa and 100kDa in Human Lung lysates after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 201kDa according to NP_056070.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About UBR2

Q8IWV8 AB002347 Q8IWV8

UBR2 Antibody, BA49A4.1 Antibody, C6orf133 Antibody, DJ392M17.3 Antibody, DJ242G1.1 Antibody, N-recognin-2 Antibody, KIAA0349 Antibody, RP3-392M17.3 Antibody

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A.

Immunohistochemistry

Immunohistochemistry
Anti-UBR2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9517 concentration 5 ug/ml.
 

Requested From: United States
Date Requested: 12/7/2016

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