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UBR2

ubiquitin protein ligase E3 component n-recognin 2

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.

Gene Name: ubiquitin protein ligase E3 component n-recognin 2
Synonyms: UBR2, BA49A4.1, C6orf133, DJ392M17.3, DJ242G1.1, N-recognin-2, KIAA0349, RP3-392M17.3
Target Sequences: AB002347 Q8IWV8 Q8IWV8

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Products
Antibodies (20)
Primary (20)
UBR2 (20)
Human (20)
Mouse (10)
Rat (6)
Bat (3)
Bovine (4)
Chicken (4)
Chimpanzee (6)
Dog (4)
Gibbon (6)
Guinea pig (3)
Hamster (4)
Horse (7)
Monkey (4)
Orangutan (3)
Pig (4)
Rabbit (4)
IHC (4)
IHC-P (1)
WB (14)
ELISA (7)
IF (1)
IP (1)
Peptide-ELISA (2)
rabbit (19)
goat (1)
Product Group
IHCPlus (1)
IgG (12)
polyclonal pc (20)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (11)
C-Terminus (4)
aa314-363 (4)
Internal (1)
aa1618-1631 (1)
aa1705-1755 (1)
No (20)
UBR2 Antibody - Anti-UBR2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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UBR2 Goat anti-Human Polyclonal (aa1618-1631) Antibody
Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
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UBR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$351
UBR2 Antibody - 1:100 staining mouse pancreas tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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UBR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
UBR2 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer tissue  using UBR2 Polyclonal Antibody at dilution of 1:55(×200)
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UBR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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UBR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
UBR2 Antibody - Detection of human and mouse UBR2 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-UBR2 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 75 seconds.
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UBR2 Rabbit anti-Human Polyclonal (aa1705-1755) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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UBR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
UBR2 Antibody - Western Blot All lanes: UBR2 antibody at 3µg/ml + Mouse liver tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 201, 50, 67 kDa Observed band size: 201 kDa
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UBR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
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UBR2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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UBR2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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UBR2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
UBR2 Antibody - MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBR2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
UBR2 Antibody - MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBR2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Horse, Gibbon, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
UBR2 Antibody - MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBR2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Horse, Gibbon, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
UBR2 Antibody - MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBR2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Horse, Gibbon, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
UBR2 Antibody - Western blot of Human Fetal Small Intestine. UBR2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBR2 Rabbit anti-Human Polyclonal (aa314-363) Antibody
Human
WB
Unconjugated
100 µl/$424
UBR2 Antibody - Western blot of Human Fetal Small Intestine. UBR2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBR2 Rabbit anti-Human Polyclonal (aa314-363) (HRP) Antibody
Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
UBR2 Antibody - Western blot of Human Fetal Small Intestine. UBR2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBR2 Rabbit anti-Human Polyclonal (aa314-363) (Biotin) Antibody
Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
UBR2 Antibody - Western blot of Human Fetal Small Intestine. UBR2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBR2 Rabbit anti-Human Polyclonal (aa314-363) (FITC) Antibody
Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
UBR2 Antibody - Western blot analysis of UBR2 expression in HepG2 (A); mouse liver (B); rat liver (C) whole cell lysates.
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UBR2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).