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Anti-Tuberin / TSC2 Antibody (N-Terminus) IHC-plus™ LS-B613

Note: This antibody replaces LS-C19506
Catalog Size Price
LS-B613-50 50 µg (1 mg/ml) Unavailable

Most Popular Tuberin / TSC2 Antibodies

Anti-Tuberin / TSC2 Antibody (N-Terminus) IHC-plus™ LS-B613
Rabbit Polyclonal to Human Tuberin / TSC2
Human, Mouse
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-Tuberin / TSC2 Antibody (phospho-Ser664) IHC-plus™ LS-B1654
Rabbit Polyclonal (IgG) to Human Tuberin / TSC2
Human
IHC - Paraffin, Immunofluorescence
Unconjugated
Immunohistochemistry Image
Anti-Tuberin / TSC2 Antibody (phospho-Ser1798) LS-C96812
Rabbit Polyclonal to Human Tuberin / TSC2
Human
Immunofluorescence, Dot Blot
Unconjugated
Immunofluorescence Image
Anti-Tuberin / TSC2 Antibody (Ser1798) IHC-plus™ LS-B6311
Rabbit Polyclonal to Human Tuberin / TSC2
Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-Tuberin / TSC2 Antibody (clone 249CT19.1.3) IHC-plus™ LS-B11230
Mouse Monoclonal [clone 249CT19.1.3] (IgG1,k) to Mouse Tuberin / TSC2
Mouse, Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed
Rabbit Polyclonal to Human Tuberin / TSC2
Human, Mouse
IHC - Paraffin, ICC, Western blot
Unconjugated

Details

Human Tuberin / TSC2
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • ICC
  • Western blot (1 µg/ml)

Specificity and Use

Tuberin / TSC2 antibody was raised against synthetic peptide from human TSC2.
LS-E30141 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-B613. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
N-Terminus
14 amino acid peptide from near the amino terminus of human TSC2
Immunohistochemistry: LS-B613 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B613 was determined to be 5 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About Tuberin / TSC2

P49815 NM_000548 NP_000539.2

TSC2 Antibody, LAM Antibody, Tuberous sclerosis 2 protein Antibody, TSC4 Antibody, Tuberin Antibody, Tuberous sclerosis 2 Antibody

Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors.

Immunohistochemistry

Immunohistochemistry
Anti-TSC2 / Tuberin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B613 concentration 5 ug/ml.

Immunocytochemistry

Immunocytochemistry
Immunocytochemistry of TSC2 in L1210 cells with TSC2 antibody at 10 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of TSC2 in L1210 cells with TSC2 antibody at 20 ug/ml.

Western blot

Western blot
Western blot of TSC2 in L1210 cell lysate with TSC2 antibody at (A) 2 and (B) 4 ug/ml.

Requested From: 
Date Requested: 6/23/2017

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