Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TLR3 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.
Anti-TLR3 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8178 dilution 5 ug/ml.
Western blot of TLR3 in male rat reproductive tissue: 1) whole testis, 2) caput, 3) corpus, 4) cauda and 5) vas deferens and mouse intestine tissue in the 6) absence and 7) presence of immunizing peptide using TLR3 antibody at 1 ug/ml.
Flow cytometry of TLR3 in RAW cells using TLR3 antibody (red) and isotype control antibody (green) at 1 ug/10^6 cells.
Requested From: United States
Date Requested: 12/4/2016