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Catalog Number Size Price
LS-C42338-0.1 0.1 mg (1 mg/ml) $410 
Antibody

Polyclonal Rabbit anti‑Human TLR3 Antibody (C‑Terminus, IHC, WB) LS‑C42338

Polyclonal Rabbit anti‑Human TLR3 Antibody (C‑Terminus, IHC, WB) LS‑C42338

Antibody:
TLR3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$410
LS-C42338-0.1
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
TLR3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
TLR3 antibody LS-C42338 is an unconjugated rabbit polyclonal antibody to human TLR3 (C-Terminus). Validated for IHC and WB.
Target
Human TLR3
Synonyms
TLR3 | CD283 | Toll-like receptor 3 | CD283 antigen | IIAE2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to a 15 amino acid sequence located near human CD283 C-Terminus
Epitope
C-Terminus
Specificity
Recognizes human CD283, otherwise known as toll receptor 3, a 103.8 kD member of the evolutionarily conserved toll-like receptor family (TLRs), expressed at high levels in the placenta and pancreas and also expressed by dendritic cells. TLRs play an important role in the recognition of invading microbial pathogens during innate immunity, acting through adaptor molecules such as MyD88 and TRAF6. CD283 acts via a cytokine signaling pathway to induce the activation of NF-kappaB and type I interferons, and has been shown to recognize double-stranded viral RNA, including that of the Influenza A and West Nile virus. Has been shown as suitable for use in IHC on EL4 cytospins at 1 ug/ml.
Applications
  • IHC - Frozen
  • Western blot (1 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Western Blot: LS-C42338 detects a band of approximately 103.8kD in human Daudi cell lysates.
Presentation
PBS, 0.02% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TLR3
O15455 NM_003265 NP_003256.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/27/2021