Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1030A5.138] (IgG1) to Human TLR2
IHC - Paraffin, Western blot, Flow Cytometry
Mouse Monoclonal [clone TLR2.45] (IgG1) to Human TLR2
Immunofluorescence (applications tested for the base form of this product only)
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [TLR2.45]
Also available conjugated with Biotin, FITC.
(applications tested for the base form of this product only)
Specificity and Use
TLR2 antibody was raised against ba/F3 cells that stably expressed human Flag-tagged TLR2
For flow cytometry and immunofluorescence dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins.