Menu
Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

TLR2

toll-like receptor 2

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

Gene Name: toll-like receptor 2
Family/Subfamily: Toll-like Receptor , not assigned-Toll-like Receptor
Synonyms: TLR2, CD282 antigen, CD282, TIL4, Toll-like receptor 2
Target Sequences: NM_003264 NP_003255.2 O60603

Publications (9)

1
High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Chavakis E, Hain A, Vinci M, Carmona G, Bianchi ME, Vajkoczy P, Zeiher AM, Chavakis T, Dimmeler S. Circulation research. 2007 100:204-12. [PubMed:17218606] Related Antibodies: LS-C40823.
2
Bacterial peptidoglycan breaks down intestinal tolerance via mast cell activation: the role of TLR2 and NOD2. Wu L, Feng BS, He SH, Zheng PY, Croitoru K, Yang PC. Immunology and cell biology. 2007 85:538-45. [PubMed:17563761] Related Antibodies: LS-C98266.
3
Vibrio vulnificus IlpA-induced cytokine production is mediated by Toll-like receptor 2. Goo SY, Han YS, Kim WH, Lee KH, Park SJ. The Journal of biological chemistry. 2007 282:27647-58. [PubMed:17640874] Related Antibodies: LS-C40823.
4
Bovine monocyte TLR2 receptors differentially regulate the intracellular fate of Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium. Weiss DJ, Souza CD, Evanson OA, Sanders M, Rutherford M. Journal of leukocyte biology. 2008 83:48-55. [PubMed:17913973] Related Antibodies: LS-C40823.
5
Monocytes differentiated with GM-CSF and IL-15 initiate Th17 and Th1 responses that are contact-dependent and mediated by IL-15. Harris KM. Journal of leukocyte biology. 2011 90:727-34. [PubMed:21724805] Related Antibodies: LS-C40823.
6
Structural determination and Toll-like receptor 2-dependent proinflammatory activity of dimycolyl-diarabino-glycerol from Mycobacterium marinum. Elass-Rochard E, Rombouts Y, Coddeville B, Maes E, Blervaque R, Hot D, Kremer L, Gurardel Y. The Journal of biological chemistry. 2012 287:34432-44. [PubMed:22798072] [PMC:PMC3464548] Related Antibodies: LS-C40823.
7
Activation of MyD88-dependent TLR1/2 signaling by misfolded a-synuclein, a protein linked to neurodegenerative disorders. Daniele SG, Béraud D, Davenport C, Cheng K, Yin H, Maguire-Zeiss KA. Science signaling. 2015 8:ra45. (WB; Mouse) [Full Text Article] [PubMed:25969543] [PMC:PMC4601639] Related Antibodies: LS-C98268.
8
A comparison of the impact of Shimen and C strains of classical swine fever virus on Toll-like receptor expression. Cao Z, Guo K, Zheng M, Ning P, Li H, Kang K, Lin Z, Zhang C, Liang W, Zhang Y. The Journal of general virology. 2015 96:1732-45. (WB; Human) [Full Text Article] [PubMed:25805409] Related Antibodies: LS-C116906.
9
VB-201, an oxidized phospholipid small molecule, inhibits CD14- and Toll-like receptor-2-dependent innate cell activation and constrains atherosclerosis. Mendel I, Feige E, Yacov N, Salem Y, Levi I, Propheta-Meiran O, Shoham A, Ishai E, George J, Harats D, Breitbart E. Clinical and experimental immunology. 2014 January;175:126-37. [Full Text Article] [PubMed:24116867] [PMC:PMC3898561] Related Antibodies: LS-C10673.
more

☰ Filters
TLR2 (272)
No (267)
Yes (5)
Viewing 1-25 of 272 items
TLR2 Antibody - Anti-TLR2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human TLR2
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $545.00
TLR2 Antibody - Anti-TLR2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human TLR2
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $485.00
TLR2 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
(1) Publication(s)
Rabbit Polyclonal to Mouse TLR2
Mouse
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Select
Rabbit Polyclonal to Human TLR2
Mouse, Bovine, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $325.00
TLR2 Antibody - Surface staining of normal human peripheral blood cells with anti-human Toll-like receptor 2 (TL2.1) PE. Appropriate isotype controls were used (open histogram). Cells in the monocyte population were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone TL2.1] (IgG2a,k) to Human TLR2
Human
Flo
APC Conjugated
25tst   $265.00; 100tst   $385.00
Select
(1) Publication(s)
Mouse Monoclonal (IgG2a) to Human TLR2
Human, Monkey
Flo, IHC, IHC-Fr, IHC-P, IP, Neut, WB
Unconjugated
100µg   $710.00
TLR2 Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with TLR2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
(1) Publication(s)
Rabbit Polyclonal to Human TLR2
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
TLR2 Antibody - TLR2 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
(1) Publication(s)
Rabbit Polyclonal to Human TLR2
Rabbit, Mouse, Goat, Sheep, Bovine, Pig, Horse, Human
WB
Unconjugated
100µl   0.5mg/ml   $365.00
Select
Mouse Monoclonal [clone 11G7] (IgG1) to Human TLR2
Human
Flo
FITC Conjugated
0.1mg   0.1mg/ml   $365.00
Select
Mouse Monoclonal (IgG2a) to Human TLR2
Human
Flo
Biotin Conjugated
100µg   $485.00
TLR2 Antibody - Human peripheral blood monocytes stained with TL2.1 FITC.
Select
(5) Publication(s)
Mouse Monoclonal [clone TL2.1] (IgG2a) to Human TLR2
Human
Flo, IHC, IP, WB
Unconjugated
100µg   0.5mg/ml   $305.00
Select
Mouse Monoclonal [clone TL2.1] (IgG2a) to Human TLR2
Dog, Human
Flo, IP, Neut
Unconjugated, Azide-free
100µg   0.5mg/ml   $335.00
TLR2 Antibody - Western blot analysis of extracts of various cell lines, using TLR2 antibody. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
Select
Rabbit Polyclonal (IgG) to Human TLR2
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
50µl   $315.00; 100µl   $425.00; 200µl   $650.00
Select
Mouse Monoclonal [clone T2.5] (IgG1) to Mouse TLR2
Mouse, Human
Flo, Func, IF, IHC, IHC-Fr, IP
Unconjugated
100µg   $575.00
Select
Mouse Monoclonal [clone TL2.1] (IgG2a) to Human TLR2
Dog, Human
Flo, Func, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100µg   $435.00
Select
Mouse Monoclonal (IgG2a) to Mouse TLR2
Mouse
ELISA, Flo, IHC, IHC-Fr, IP
Unconjugated
100µg   $710.00
TLR2 Antibody - Western blot of recombinant TLR2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Rat TLR2
Rat
WB
Unconjugated
20µl   0.5mg/ml   $205.00; 100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $295.00; 1ml   0.5mg/ml   $515.00
Select
Mouse Monoclonal [clone TL2.3] (IgG2a) to Human TLR2
Human
ELISA, ICC, IHC, IHC-Fr
Unconjugated
100µg   1mg/ml   $345.00
Select
Mouse Monoclonal (IgG1) to Human TLR2
Human
Flo, Func, IF, IP
Unconjugated
100µg   $710.00
Select
Mouse Monoclonal (IgG2a) to Human TLR2
Human, Monkey, Cynomolgus
Flo, IHC, IHC-Fr, IHC-P, IP, WB
FITC Conjugated
100µg   $800.00
Select
Mouse Monoclonal (IgG2a) to Human TLR2
Human
Flo, IHC, IHC-Fr
Unconjugated
100µg   $575.00
Select
Rat Monoclonal [clone IMG11G5] (IgG2a,k) to Mouse TLR2
Mouse
Flo, WB
Unconjugated
100µg   0.5mg/ml   $335.00
Select
Mouse Monoclonal [clone 11G7] (IgG) to Human TLR2
Human
ELISA, Flo, IP
Biotin Conjugated
100µg   $255.00
Select
Mouse Monoclonal (IgG2a) to Human TLR2
Human
Flo
Unconjugated
100µg   $475.00
TLR2 Antibody - Western blot of mTLR2 in 15 ul/lane of transfected cell lysate using antibody at 1 ug/ml.
Select
Rabbit Polyclonal (IgG) to Mouse TLR2
Mouse
WB
Unconjugated
100µg   200µl   0.5mg/ml   $335.00

Viewing 1-25 of 272 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).