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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.
TCR Screening ServicesTest your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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TLR2
toll-like receptor 2
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.
| Gene Name: | toll-like receptor 2 |
| Family/Subfamily: | Toll-like Receptor , not assigned-Toll-like Receptor |
| Synonyms: | TLR2, CD282 antigen, CD282, TIL4, Toll-like receptor 2 |
| Target Sequences: | NM_003264 NP_003255.2 O60603 |
Publications (9)
1
High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Chavakis E, Hain A, Vinci M, Carmona G, Bianchi ME, Vajkoczy P, Zeiher AM, Chavakis T, Dimmeler S. Circulation research. 2007 100:204-12.
[PubMed:17218606]
Related Antibodies: LS-C40823.
2
Bacterial peptidoglycan breaks down intestinal tolerance via mast cell activation: the role of TLR2 and NOD2. Wu L, Feng BS, He SH, Zheng PY, Croitoru K, Yang PC. Immunology and cell biology. 2007 85:538-45.
[PubMed:17563761]
Related Antibodies: LS-C98266.
3
Vibrio vulnificus IlpA-induced cytokine production is mediated by Toll-like receptor 2. Goo SY, Han YS, Kim WH, Lee KH, Park SJ. The Journal of biological chemistry. 2007 282:27647-58.
[PubMed:17640874]
Related Antibodies: LS-C40823.
☰ Filters
Products
Antibodies
(248)
Type
Primary
(248)
Target
TLR2
(248)
Reactivity
Human
(205)
Mouse
(78)
Rat
(16)
Bovine
(4)
Chimpanzee
(6)
Cynomolgus
(1)
Dog
(15)
Gibbon
(3)
Goat
(4)
Horse
(4)
Monkey
(12)
Orangutan
(3)
Pig
(4)
Rabbit
(5)
Sheep
(4)
Application
IHC
(81)
IHC-Fr
(34)
IHC-P
(28)
WB
(151)
Flo
(117)
Block
(1)
ELISA
(51)
Func
(14)
ICC
(12)
IF
(27)
IP
(55)
Neut
(2)
Host
rabbit
(102)
mouse
(132)
goat
(3)
chicken
(1)
rat
(10)
Product Group
IHCPlus
(2)
Isotype
IgG
(75)
IgG1
(25)
IgG1,k
(13)
IgG2a
(66)
IgG2a,k
(7)
IgG2b
(11)
Clonality
monoclonal mc
(146)
polyclonal pc
(102)
Clone
067
(4)
1070CT4.2.3.2
(1)
11
(1)
11G7
(7)
13A73
(1)
2B4A1
(6)
2G9
(1)
67N17F8
(1)
67N8F8
(2)
6C2
(4)
7C1H9
(1)
7G5F4
(1)
8F11G10
(1)
ABM3A87
(4)
GF1
(1)
IMG11G5
(2)
m T2.4
(1)
mT2.7
(5)
MT2.7
(2)
T2.5
(2)
TL2.1
(14)
TL2.3
(7)
TLR2.45
(3)
TLR2/221
(2)
Format
AP Conjugated
(6)
APC
(6)
APC Conjugated
(15)
Azide-free
(14)
Biotin Conjugated
(32)
Concentrated
(6)
Cy3 Conjugated
(6)
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(6)
FITC Conjugated
(38)
HRP Conjugated
(15)
Low Endotoxin
(1)
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(22)
Preservative Free
(2)
RPE Conjugated
(6)
Unconjugated
(102)
Epitope
aa47-245
(24)
aa212-242
(8)
aa25-250
(8)
aa281-310
(8)
aa595-760
(8)
aa644-784
(8)
aa720-749
(8)
aa 180-420
(4)
aa180-229
(4)
aa591-640
(4)
aa180-196
(3)
N-Terminus
(2)
aa227-398
(2)
aa400-450
(2)
C-Terminus
(1)
Extracellular Domain
(1)
N-Terminal
(1)
aa221-384
(1)
aa227-397
(1)
aa364-379
(1)
aa564-580
(1)
Publications
No
(243)
Yes
(5)
TLR2 Rabbit anti-Mouse Polyclonal (aa720-749) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
400 µl/$325
TLR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$545
TLR2 Mouse anti-Human Monoclonal Antibody
Human, Monkey
Flo, IHC, IHC-Fr, IHC-P, IP, Neut, WB
Unconjugated
100 µg/$710
TLR2 Rabbit anti-Human Polyclonal (aa591-640) Antibody
Rabbit, Mouse, Goat, Sheep, Bovine, Pig, Horse, Human
WB
Unconjugated
100 µl/$365
TLR2 Rabbit anti-Human Polyclonal (aa212-242) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$325
TLR2 Mouse anti-Human Monoclonal (FITC) (11G7) Antibody
Human
Flo
FITC Conjugated
0.1 mg/$365
TLR2 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo
Biotin Conjugated
100 µg/$485
TLR2 Mouse anti-Human Monoclonal (TL2.1) Antibody
Human
Flo, IHC, IP, WB
Unconjugated
100 µg/$305
TLR2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$485
TLR2 Mouse anti-Human Monoclonal (aa227-398) (67N8F8) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µg/$335
TLR2 Rat anti-Mouse Monoclonal Antibody
Mouse
Flo, Func, IF, IP
Unconjugated
100 µg/$710
TLR2 Mouse anti-Human Monoclonal (Azide-free) (TL2.1) Antibody
Dog, Human
Flo, IP, Neut
Unconjugated, Azide-free
100 µg/$335
TLR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
20 µl/$215; 50 µl/$315; 100 µl/$425; 200 µl/$650
TLR2 Mouse anti-Mouse Monoclonal (T2.5) Antibody
Mouse, Human
Flo, Func, IF, IHC, IHC-Fr, IP
Unconjugated
100 µg/$590; 500 µg/$1,365
TLR2 Mouse anti-Human Monoclonal (TL2.1) Antibody
Dog, Human
Flo, Func, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$445; 500 µg/$1,095
TLR2 Mouse anti-Mouse Monoclonal Antibody
Mouse
ELISA, Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$710
TLR2 Rabbit anti-Rat Polyclonal (aa595-760) Antibody
Rat
WB
Unconjugated
100 µl/$255; 200 µl/$295; 500 µl/$435; 1 ml/$515
TLR2 Mouse anti-Human Monoclonal Antibody
Human
Flo, Func, IF, IP
Unconjugated
100 µg/$710
TLR2 Mouse anti-Human Monoclonal (FITC) Antibody
Human, Monkey, Cynomolgus
Flo, IHC, IHC-Fr, IHC-P, IP, WB
FITC Conjugated
100 µg/$800
TLR2 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated
100 µg/$590
TLR2 Rat anti-Mouse Monoclonal (aa400-450) (IMG11G5) Antibody
Mouse
Flo, WB
Unconjugated
100 µg/$335
TLR2 Mouse anti-Human Monoclonal (Biotin) (11G7) Antibody
Human
ELISA, Flo, IP
Biotin Conjugated
100 µg/$255
TLR2 Mouse anti-Human Monoclonal Antibody
Human
Flo
Unconjugated
100 µg/$475
TLR2 Rabbit anti-Mouse Polyclonal (aa564-580) Antibody
Mouse, Human
WB
Unconjugated
100 µg/$335
Viewing 1-25
of 248
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
