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Anti-RNF139 / TRC8 Antibody (clone 3D10) LS-C133685


Wt. Vol. Conc. Price
100 µg - - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular RNF139 / TRC8 Antibodies

Anti-RNF139 / TRC8 Antibody (aa72-121) IHC-plus™ LS-B8095
Rabbit Polyclonal (IgG) to Human RNF139 / TRC8
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Rabbit
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-RNF139 / TRC8 Antibody (aa651-663) IHC-plus™ LS-B8293
Goat Polyclonal to Human RNF139 / TRC8
Human, Monkey
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image
Anti-RNF139 / TRC8 Antibody (aa565-665, APC) LS-C226494
Mouse Monoclonal (IgG1) to Human RNF139 / TRC8
IHC, Western blot, ELISA
APC Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 3D10] (IgG1,k) to Human RNF139 / TRC8
Western blot, ELISA


Human RNF139 / TRC8
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [3D10]
Protein A purified


  • Western blot

Specificity and Use

RNF139 / TRC8 antibody was raised against rNF139 (NP_009149, 565 a.a. ~ 665 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Human RNF139
Sandwich ELISA: Recombinant protein. Western Blot: Cell lysate, Recombinant protein.


PBS, pH 7.2
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
For research use only.

About RNF139 / TRC8

Q8WU17 NM_007218 NP_009149.2

RNF139 Antibody, HRCA1 Antibody, RCA1 Antibody, TRC8 Antibody, Ring finger protein 139 Antibody

E3-ubiquitin ligase; acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination.

Western blot

Western blot
RNF139 monoclonal antibody (M01), clone 3D10 Western blot of RNF139 expression in HepG2.

Enzyme-Linked Immunosorbent Assay

Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged RNF139 is approximately 0.03 ng/ml as a capture antibody.

Requested From: United States
Date Requested: 10/28/2016

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