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Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Gene Name: | nestin |
Synonyms: | NES, Nestin, Nbla00170 |
Target Sequences: | X65964 CAA46780.1 P48681 |
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