Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG1) to Mouse MEIS1/MEIS2/MEIS3
IHC - Paraffin, Western blot, Immunoprecipitation
Mouse, Human (tested or 100% immunogen sequence identity)
IHC - Paraffin (1:1000 - 1:5000)
Western blot (1:1000 - 1:5000)
Specificity and Use
MBP-conjugated fusion protein corresponding to amino acids 60-390 of mouse Meis1.
Recognizes Meis1, Meis2, Meis3 and splice variants, Mr ~45-66kD. Species cross-reactivity: Human and mouse.
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Western Blot: 1:1000-1:5000 detects Meis in nuclear extract from K562 cells. K562 nuclear extract was resolved by electrophoresis, transferred to nitrocellulose and probed with anti-Meis 1/2/3 (1:2500 dilution). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Meis (~54kD and 66kD). Immunohistochemistry: Detects Meis in mouse embryo paraffin sections. Immunoprecipitation: Immunoprecipitates Meis from NIH-3T3 nuclear extract.