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Anti-MCAM / CD146 Antibody LS-C149995

Ordering

Wt. Vol. Conc. Price
100 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MCAM / CD146 Antibodies

Anti-MCAM / CD146 Antibody (aa19-560) LS-C35841
Mouse Monoclonal (IgG2a) to Rat MCAM / CD146
Rat
Western blot, Flow Cytometry, ELISA
Unconjugated
Anti-MCAM / CD146 Antibody (clone P1H12) IHC-plus™ LS-B4050
Mouse Monoclonal [clone P1H12] (IgG1) to Human MCAM / CD146
Human
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Human MCAM / CD146
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human MCAM / CD146
Goat
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 - 15 µg/ml)
  • Western blot (0.1 µg/ml)

Specificity and Use

MCAM / CD146 antibody was raised against mouse myeloma cell line NS0-derived recombinant human MCAM/CD146 Met1-Gly559 Accession # AAA20824.
Detects human MCAM/CD46 in Western blots and direct ELISAs. In Western blots, approximately 15% cross-reactivity with recombinant.
Western Blot, 0.1 µg/ml, Recombinant Human MCAM/CD146. Immunohistochemistry, 5-15 µg/ml.

Packaging

Lyophilized from 0.2 um filtered solution in PBS, trehalose
Sterile PBS. Resuspend to 500 ul
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About MCAM / CD146

P43121 NM_006500 NP_006491.2

MCAM Antibody, CD146 Antibody, CD146 antigen Antibody, Gicerin Antibody, Melanoma adhesion molecule Antibody, MUC18 Antibody, p1h12 Antibody

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development.

Immunohistochemistry

Immunohistochemistry
MCAM/CD146 in Human Melanoma. MCAM/CD146 was detected in immersion fixed paraffin-embedded sections of human melanoma tissue using Human MCAM/CD146 Antigen Affinity-purified Polyclonal Antibody at 5 ug/ml overnight at 4°C. Tissue was stained using Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

Immunohistochemistry

Immunohistochemistry
MCAM/CD146 in Human Melanoma. MCAM/CD146 was detected in immersion fixed paraffin-embedded sections of human melanoma tissue using Human MCAM/CD146 Antigen Affinity-purified Polyclonal Antibody at 15 ug/ml overnight at 4°C. Tissue was stained using Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

Requested From: United States
Date Requested: 12/4/2016

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