LSBio
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Biochemicals
  • All Biochemicals

  • Immunohistochemistry
  • Immunohistochemistry Reagents
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Research Areas
  • Cancer Research Resources and Products:
  • Breast Cancer
  • Colorectal Cancer
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Reviews
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure ShareFile Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login ▾
Wish List
View Cart

Anti-MCAM / CD146 Antibody LS-C14266

Catalog Size Price
LS-C14266-200 200 µg Unavailable

Related Products

159 MCAM / CD146 Antibodies

Most Popular MCAM / CD146 Antibodies

Anti-MCAM / CD146 Antibody (aa433-647) LS-C33782
Rabbit Polyclonal to Human MCAM / CD146
Human
IHC
Unconjugated
Angioscarcoma stained with anti-CD146
Anti-MCAM / CD146 Antibody (aa19-560) LS-C35841
Mouse Monoclonal (IgG2a) to Rat MCAM / CD146
Rat
Western blot, Flow Cytometry, ELISA
Unconjugated
Anti-MCAM / CD146 Antibody (Tyr641) IHC-plus™ LS-B3628
Rabbit Polyclonal to Human MCAM / CD146
Human
IHC, IHC - Paraffin, Western blot
Unconjugated
Anti-MCAM / CD146 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3628 concentration 10 ug/ml.
Anti-MCAM / CD146 Antibody (clone P1H12) IHC-plus™ LS-B4050
Mouse Monoclonal [clone P1H12] (IgG1) to Human MCAM / CD146
Human
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-MCAM / CD146 antibody IHC of human vessels in human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4050 concentration 20 ug/ml.
Anti-MCAM / CD146 Antibody (aa532-558, PE) LS-C262812
Rabbit Polyclonal (IgG) to Human MCAM / CD146
Human
IHC, Western blot, ELISA
PE Conjugated

100% Guaranteed
Mouse Monoclonal (IgG1,k) to Human MCAM / CD146
Human
IHC, ICC, Western blot, Immunoprecipitation (applications tested for the base form of this product only)
Unconjugated

Details

Human MCAM / CD146
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Protein G purified
Unmodified

Applications

  • IHC
  • ICC
  • Western blot (1 - 2 µg/ml)
  • Immunoprecipitation
  • (applications tested for the base form of this product only)

Specificity and Use

MCAM / CD146 antibody was raised against human primary WM902B melanoma cells.
Recognizes MEL-CAM, also known as MUC18, CD146, S-Endo-1, or A32 melanomaassociated antigen, Mr ~113kD. Species cross-reactivity: Human specific.
Suitable for use in Western Blot, Immunohistochemistry, Immunoprecipitation and Immunocytochemistry. Western Blot: 1-2 ug/ml detected MEL-CAM lysates from SK-Mel-37 melanoma cell lysates. SK-Mel-37 cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with anti-MEL-CAM (MUC18, CD146) (1 ug/ml). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunohistochemistry: Detects MEL-CAM in human melanoma samples by PAP immunohistochemistry. Immunoprecipitation: Reported by an independent laboratory to immunoprecipitate MEL-CAM from WM1366 melanoma cell lysates. Immunocytochemistry: Detects MEL-CAM in human keratinocytes.

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About MCAM / CD146

P43121 NM_006500 NP_006491.2

MCAM Antibody, CD146 Antibody, CD146 antigen Antibody, Gicerin Antibody, Melanoma adhesion molecule Antibody, MUC18 Antibody, p1h12 Antibody

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development.

Requested From: 
Date Requested: 5/25/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number