Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Western blot (1 - 10 µg/ml)
ELISA (1:10000 - 1:100000)
MC1R antibody was raised against synthetic peptide corresponding to 21aa near the C-terminus of mouse MC1-R (KLH). Cellular localization: Cytoplasmic domain
The 21 AA mouse immunogenic peptide shows homology of with human (15/21 aa; 71%), equine (14/21; 66%), bovine (14/21; 66%), sheep (14/21; 66%) and Red Fox (12/20; 60%). Actual cross-reactivity of antibodies in all species is not established.
Suitable for use in ELISA and Western Blot. Western Blot: 1-10 ug/ml using ECL. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well.
PBS, pH 7.4, 0.1% BSA
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color.