Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG1) to Human IL6ST / CD130 / gp130
Flow Cytometry, ELISA (applications tested for the base form of this product only)
Human IL6ST / CD130 / gp130
Human (tested or 100% immunogen sequence identity)
Also available conjugated with AP, HRP, PE.
Ion exchange chromatography
(applications tested for the base form of this product only)
Specificity and Use
Natural soluble gp130 receptor.
Recognizes soluble and membrane bound human gp130 receptor. This antibody has been reported to block the activity of IL-6.
Suitable for use in ELISA and Flow Cytometry. Flow Cytometry: 0.2 ug/1E6 cells. Use 20 ul to label 1E6 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, pH 7.2, 0.09% sodium azide, 40% glycerol.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
IL6ST / CD130 / gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors.