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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IL6ST / CD130 / gp130 Antibody (RPE) LS‑C14205
Gp130 antibody LS-C14205 is an RPE-conjugated mouse monoclonal antibody to human gp130 (IL6ST / CD130). Validated for ELISA and Flow.
Antibody
Catalog
Size
Price
LS-C14205-100
100 µg (0.5 mg/ml)
$650

Popular IL6ST / CD130 / gp130 Products

Antibody
Species: Human, Monkey, Mouse
Applications: Western blot, ELISA
Staining of BALB/c splenocytes with FITC anti-mouse CD3e (145-2C11) (LS-C105774) and 0.125 ug of Purified anti-mouse gp130 (KGP130)followed by PE Anti-Rat IgG (LS-C106534). Cells in the lymphocyte gate were used for analysis.
Species: Mouse
Applications: Western blot, Flow Cytometry
CD130 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human uterus tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CD130/gp130 Antibody. The picture on the right is blocked with the synthesized peptide.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay

Product Description

Gp130 antibody LS-C14205 is an RPE-conjugated mouse monoclonal antibody to human gp130 (IL6ST / CD130). Validated for ELISA and Flow.
About IL6ST / CD130 / gp130
IL6ST / CD130 / gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. P40189 NM_002184 NP_002175.2

IL6ST Antibody, CD130 Antibody, CD130 antigen Antibody, IL-6R subunit beta Antibody, IL-6 receptor subunit beta Antibody, Membrane glycoprotein gp130 Antibody, Membrane glycoprotein 130 Antibody, IL-6RB Antibody, CDW130 Antibody, gp130 Antibody, IL-6R-beta Antibody


Specifications

Target
Human IL6ST / CD130 / gp130
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
R. Phycoerythrin. Also available conjugated with AP, HRP, PE.
Purification
Ion exchange chromatography
Modifications
Unmodified
Applications
  • Flow Cytometry
  • ELISA
  • (applications tested for the base form of this product only)
Immunogen
Natural soluble gp130 receptor.
Specificity
Recognizes soluble and membrane bound human gp130 receptor. This antibody has been reported to block the activity of IL-6.
Usage
Suitable for use in ELISA and Flow Cytometry. Flow Cytometry: 0.2 ug/1E6 cells. Use 20 ul to label 1E6 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.2, 0.09% Sodium Azide, 40% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/17/2018

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