Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Reasearch Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

IL6ST / CD130 / gp130

interleukin 6 signal transducer (gp130, oncostatin M receptor)

IL6ST / CD130 / gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.

Gene Name: interleukin 6 signal transducer (gp130, oncostatin M receptor)
Family/Subfamily: Interleukin
Synonyms: IL6ST, CD130, CD130 antigen, IL-6R subunit beta, IL-6 receptor subunit beta, Membrane glycoprotein gp130, Membrane glycoprotein 130, IL-6RB, CDW130, gp130, IL-6R-beta
Target Sequences: NM_002184 NP_002175.2 P40189

Filtered by: None
Target
IL6ST / CD130 / gp130 (90)
Reactivity
Human (63)
Mouse (29)
Rat (17)
Chicken (1)
Chimpanzee (3)
Gibbon (3)
Horse (4)
Monkey (6)
Pig (5)
Rabbit (4)
Rhesus monkey (1)
Application
IHC (15)
IHC-P (5)
WB (59)
Flo (14)
DB (8)
ELISA (30)
ICC (2)
IF (6)
IP (2)
Peptide-ELISA (1)
Host
rabbit (71)
mouse (16)
rat (2)
sheep (1)
Isotype
IgG (23)
IgG1 (10)
IgG2a (3)
IgG2a,k (2)
Clonality
monoclonal mc (18)
polyclonal pc (72)
Clone
11n80 (1)
4A4 (1)
AN-G30 (1)
B-T2 (3)
RM1 (2)
Format
AP Conjugated (3)
APC (4)
APC Conjugated (6)
Azide-free (2)
Biotin Conjugated (9)
CF Conjugated (1)
Concentrated (1)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (9)
HRP Conjugated (8)
PE Conjugated (9)
RPE Conjugated (1)
Unconjugated (36)
Epitope
aa238-500 (8)
aa392-566 (8)
aa606-756 (8)
aa871-899 (8)
pTyr905 (8)
aa158-207 (4)
C-Terminus (2)
720-800 aa (1)
Extracellular Domain (1)
aa23-618 (1)
aa748-797 (1)
aa750-800 (1)
aa868-918 (1)
Publications
No (90)
Showing 1-25 of 90 results

IHC-plus™ IL6ST / CD130 / gp130 Antibody (aa750-800) LS-B10905
Rabbit Polyclonal to Human IL6ST / CD130 / gp130
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl  $425.00
Anti-CD130 / IL6ST / gp130 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Western blot of gp130 (S778) pAb in extracts from Jurkat cells.

IL6ST / CD130 / gp130 Antibody (phospho-Tyr905) LS-C327652
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Human
DB
Unconjugated
200µl 0.68mg/ml  $590.00

IL6ST / CD130 / gp130 Antibody (aa748-797) LS-C198749
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CD130/gp130 Antibody. The picture on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of NIH/3T3 cells, using CD130/gp130 Antibody. The picture on the right is blocked with the synthesized peptide.

IL6ST / CD130 / gp130 Antibody LS-C417514
Rabbit Polyclonal to Human IL6ST / CD130 / gp130
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µg  $305.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

IL6ST / CD130 / gp130 Antibody (aa871-899) LS-C168512
Rabbit Polyclonal to Human IL6ST / CD130 / gp130
Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
CD130 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human uterus tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
CD130 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The CD130 antibody detected the CD130 protein (arrow).

IL6ST / CD130 / gp130 Antibody (C-Terminus) LS-C23977
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Mouse, Human, Monkey
ELISA, WB
Unconjugated
100µl  $530.00

IL6ST / CD130 / gp130 Antibody LS-C808651
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Immunohistochemistry Image

IL6ST / CD130 / gp130 Antibody (clone AN-G30, Biotin) LS-C106189
Mouse Monoclonal [clone AN-G30] (IgG2a) to Human IL6ST / CD130 / gp130
Human
Flo
Biotin Conjugated
25µg 0.5mg/ml  $235.00; 100µg  $325.00
Staining of normal human peripheral blood cells with APC anti-human CD3 (UCHT1) (LS-C107411) and 0.06 ug of Biotin Mouse IgG2a, K Isotype Control (left) or 0.06 ug of Biotin anti-human gp130 (right) followed by Streptavidin-PE. Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL6ST / CD130 / gp130 Antibody (aa158-207) LS-C151513
Rabbit Polyclonal to Human IL6ST / CD130 / gp130
Rabbit, Pig, Horse, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
CD130 / IL6ST / gp130 antibody Western Blot of MDA-MB-435S.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL6ST / CD130 / gp130 Antibody (aa158-207, FITC) LS-C470493
Rabbit Polyclonal to Human IL6ST / CD130 / gp130
Rabbit, Pig, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $385.00
CD130 / IL6ST / gp130 antibody Western Blot of MDA-MB-435S.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL6ST / CD130 / gp130 Antibody (phospho-Tyr905) LS-C163620
Rabbit Polyclonal to Human IL6ST / CD130 / gp130
Human
DB
Unconjugated
400µl  $325.00
Dot blot of anti-Phospho-IL6ST-Y905 Phospho-specific antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

IL6ST / CD130 / gp130 Antibody (720-800 aa) LS-C382512
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of CD130 antibody

IL6ST / CD130 / gp130 Antibody LS-C487680
Rabbit Polyclonal to Rhesus monkey IL6ST / CD130 / gp130
Rhesus monkey
ICC, IF, IHC, IHC-P
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

IL6ST / CD130 / gp130 Antibody (clone RM1) LS-C179280
Rat Monoclonal [clone RM1] (IgG2a) to Mouse IL6ST / CD130 / gp130
Mouse
ELISA, Flo, IP, WB
Unconjugated
100µg 100µl 1mg/ml  $365.00
Flow Cytometry Image

IL6ST / CD130 / gp130 Antibody (aa871-899) LS-C329336
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

IL6ST / CD130 / gp130 Antibody (aa871-899, Biotin) LS-C253859
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Human
ELISA, IHC, WB
Biotin Conjugated
200µl  $740.00

IL6ST / CD130 / gp130 Antibody (aa871-899, FITC) LS-C253863
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

IL6ST / CD130 / gp130 Antibody (aa871-899, AP) LS-C253857
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Human
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

IL6ST / CD130 / gp130 Antibody (aa871-899, APC) LS-C253858
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Human
ELISA, IHC, WB
APC Conjugated
200µl  $740.00

IL6ST / CD130 / gp130 Antibody (aa871-899, Azide-free, HRP) LS-C253865
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

IL6ST / CD130 / gp130 Antibody (aa871-899, PE) LS-C253867
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Human
ELISA, IHC, WB
PE Conjugated
200µl  $740.00

IL6ST / CD130 / gp130 Antibody (clone B-T2) LS-C43306
Mouse Monoclonal [clone B-T2] (IgG1) to Human IL6ST / CD130 / gp130
Human
ELISA, Flo
Unconjugated
0.1mg  $435.00

IL6ST / CD130 / gp130 Antibody (clone B-T2) LS-C127949
Mouse Monoclonal [clone B-T2] (IgG1) to Human IL6ST / CD130 / gp130
Human
ELISA, Flo
Unconjugated
100µg  $1,110.00

IL6ST / CD130 / gp130 Antibody (clone B-T2, Concentrated) LS-C202292
Mouse Monoclonal [clone B-T2] (IgG1) to Human IL6ST / CD130 / gp130
Human
ELISA, Flo
Unconjugated, Concentrated
0.1mg  $830.00

IL6ST / CD130 / gp130 Antibody LS-C496668
Rabbit Polyclonal (IgG) to Human IL6ST / CD130 / gp130
Human
IHC, WB
Unconjugated
100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of MDA-MB231 cells, using IL6ST antibody. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
Showing 1-25 of 90 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).