Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 3E1] (IgG1) to Human IL-1B / IL-1 Beta
IHC - Paraffin, Immunofluorescence, Western blot
Rat Monoclonal [clone 11n92] (IgG2b) to Mouse IL-1B / IL-1 Beta
Mouse IL-1B / IL-1 Beta
Mouse (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [11n92]
Protein G purified
Specificity and Use
Recombinant corresponding to mouse interleukin 1 beta (rmIL-1b) expressed in E. coli.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
1ml saline, 0.5% BSA, 0.1% sodium azide
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. CFS conjugates are sensitive to light.
IL-1 Beta is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.