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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ICAM‑1 / CD54 Antibody (aa28‑483) LS‑C182567
Antibody
CD54 antibody LS-C182567 is an unconjugated sheep monoclonal antibody to human CD54 (ICAM-1). Validated for DB, ELISA, IHC and WB.
Catalog
Size
Price
LS-C182567-100
100 µg
Unavailable

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Flow cytometry of ICAM1 / CD54 antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
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Flow cytometry of ICAM1 / CD54 antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
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Applications: Flow Cytometry, ELISA

Product Description

CD54 antibody LS-C182567 is an unconjugated sheep monoclonal antibody to human CD54 (ICAM-1). Validated for DB, ELISA, IHC and WB.
About ICAM-1 / CD54
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. P05362 NM_000201 NP_000192.2

ICAM1 Antibody, BB2 Antibody, CD54 antigen Antibody, CD54 Antibody, ICAM-1 Antibody, p3.58 Antibody


Specifications

Target
Human ICAM-1 / CD54
Host
Sheep
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Monoclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • ELISA
  • Dot Blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ICAM-1 / CD54 antibody was raised against recombinant corresponding to aa28-483 from mature extracellular domain of human ICAM1, fused to 6x His-tag at N-terminal, expressed in E. coli.
Epitope
aa28-483
Specificity
Intercellular Adhesion Molecule 1.
Presentation
PBS, pH 7.2, 0.09% sodium azide
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/23/2018

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