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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Histone H3 Antibody (Mono‑Methyl‑Arg2) LS‑C7429
Antibody
Histone H3 antibody LS-C7429 is an unconjugated rabbit polyclonal antibody to human Histone H3. Validated for ICC, IHC and WB.
Catalog
Size
Price
LS-C7429-100
100 µl
Unavailable

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Product Description

Histone H3 antibody LS-C7429 is an unconjugated rabbit polyclonal antibody to human Histone H3. Validated for ICC, IHC and WB.
About Histone H3
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones.

Specifications

Target
Human Histone H3
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • ICC
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Histone H3 antibody was raised against synthetic methyl-Arg2 peptide corresponding to residues surrounding Arg2 of human histone H3 (KLH).
Epitope
Mono-Methyl-Arg2
Specificity
Recognizes human histone H3 only when methylated at Arg2 at 17kD. Does not cross-react with other histone members. Note: Adherence to the attached protocol is extremely important.
Usage
Western Blot: 1:1000. Immunohistochemistry (Paraffin): 1:50. Immunocytochemistry (ABC) 1:50.
Presentation
10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol. No preservative added.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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