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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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Catalog Number Size Price
LS-C144555-50 50 µg $285 
LS-C144555-100 100 µg (1 mg/ml) $345 
Antibody

Monoclonal Mouse anti‑Human Histone H3 Antibody (clone 7C10, Citrulline‑Arg2/8/17, IF) LS‑C144555

Monoclonal Mouse anti‑Human Histone H3 Antibody (clone 7C10, Citrulline‑Arg2/8/17, IF) LS‑C144555

Antibody:
Mouse Monoclonal to Human Histone H3
Application:
ICC, IF, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$285 
LS-C144555-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Mouse Monoclonal to Human Histone H3
Application:
ICC, IF, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Histone H3 antibody LS-C144555 is an unconjugated mouse monoclonal antibody to human Histone H3 (Citrulline-Arg2/8/17). Validated for ELISA, Flow, ICC and IF. Cited in 2 publications.
Target
Human Histone H3
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Clone
7C10
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • ICC (1:100 - 1:500)
  • Immunofluorescence (1:100 - 1:500)
  • Flow Cytometry
  • ELISA
Immunogen
Synthetic peptide derived from Nter domain of human Histone H3 containing Citrulline at position 2-8-17.
Epitope
Citrulline-Arg2/8/17
Specificity
Monoclonal antibody reacts specifically with human Histone H3 Citrulline at the 3 positions: 2, 8 and 17 The antibody doesn't react with mono or bis H3-Cit
Presentation
Lyophilized from PBS, 0.02% Sodium Azide
Reconstitution
Reconstitute with distilled water.
Storage
Store lyophilized at -20°C for 2 years. Stable at 4°C for up to 1 month or for 6 months in aliquots at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

LSBio Ratings

Histone H3 Antibody (Citrulline-Arg2/8/17, clone 7C10) for ICC, IF/Immunofluorescence, Flow, ELISA LS-C144555 has an LSBio Rating of
Publications (4.1)

Publications (2)

Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes. Vecchio F, Lo Buono N, Stabilini A, Nigi L, Dufort MJ, Geyer S, Rancoita PM, Cugnata F, Mandelli A, Valle A, Leete P, Mancarella F, Linsley PS, Krogvold L, Herold KC, Elding Larsson H, Richardson SJ, Morgan NG, Dahl-Jørgensen K, Sebastiani G, Dotta F, Bosi E; DRI_Biorepository Group; Type 1 Diabetes TrialNet Study Group, Battaglia M. JCI insight. 2018 September;3:pii: 122146.

Increased Mortality in Mice following Immunoprophylaxis Therapy with High Dosage of Nicotinamide in Burkholderia Persistent Infections. Micheva-Viteva SN, Ross BN, Gao J, Adikari S, Zhang P, Mourant JR, Wu TH, Werner JH, Torres AG, Hong-Geller E. Infection and immunity. 2018 December;87:pii e00592-18.

Customer Reviews (0)


Requested From: United States
Date Requested: 6/3/2020