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Anti-GDF15 Antibody (C-Terminus) LS-C154238


Wt. Vol. Conc. Price
100 µg - - $405
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular GDF15 Antibodies

Anti-GDF15 Antibody (aa286-299) IHC-plus™ LS-B2413
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Anti-GDF15 Antibody (clone ME-6D10) LS-C89472
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Anti-GDF15 Antibody (clone 6D12.H10.E4) IHC-plus™ LS-B8327
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IHC - Paraffin, Western blot, ELISA
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100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human GDF15
Human, Mouse
Western blot, ELISA


Human GDF15
Human, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • Western blot (1:2000 - 1:10000)

Specificity and Use

GDF15 antibody was raised against this affinity purified antibody was prepared by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminal end of human NAG-1 protein. A residue of cysteine was added to facilitate coupling to KLH.
This antibody reacts with the C-terminus of endogenous NAG-1 protein from human and mouse tissues. A BLAST analysis suggests reactivity with NAG-1 from chimpanzee and macaque based on a 100% homology. Partial reactivity is expected against rat based on an 86% homology with the immunizing sequence. Cross-reactivity with NAG-1 from other sources has not been determined.
This affinity purified antibody is suitable for ELISA and western blotting of human and mouse NAG-1 protein. For detection of NAG-1 in human serum, a sandwich ELISA is suggested using this antibody in combination with anti-NAG-1/GDF15 (N-terminal), H variant or D variant specific antibodies. Specific conditions for reactivity should be optimized by the end user. Expect bands in Western blots of approximately 14 and 28 kD in size corresponding to NAG-1 monomer and dimer, respectively, using the appropriate cell lysate or extract.


0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide, sterile filtered
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About GDF15

Q99988 NM_004864 NP_004855.2

GDF15 Antibody, MIC1 Antibody, MIC-1 Antibody, NAG-1 Antibody, NRG-1 Antibody, NSAID-regulated gene 1 protein Antibody, PLAB Antibody, NSAID-activated gene 1 protein Antibody, Placental TGF-beta Antibody, PTGFB Antibody, GDF-15 Antibody, PTGF-beta Antibody

Growth differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB. GDF15 mRNA is most abundant in the liver, with lower levels seen in some other tissues.

Western blot

Western blot
Anti-NAG-1/GDF15 (C-terminal) Antibody - Western Blot. Western blot of affinity purified anti-NAG-1/GDF15 (C-terminal) antibody shows detection NAG-1 purified from CHO cells as a 14 kD band corresponding to monomer and a 28 kD band corresponding to dimerized NAG-1. Samples were electrophoresed on a 4-20% gradient gel under reducing conditions. Lane 1 shows NAG-1 detection. Lane 2 shows reactivity is blocked when this antibody is pre-incubated with the immunizing peptide prior to Western blotting.

Requested From: United States
Date Requested: 10/24/2016

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