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Anti-FFAR2 / GPR43 Antibody (C-Terminus) IHC-plus™ LS-A6598

Catalog Size Price
LS-A6598-50 50 µg (1 mg/ml) Unavailable
Same day shipping In Stock - Same day shipping

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100% Guaranteed In Stock Publications (1)
Rabbit Polyclonal to Human FFAR2 / GPR43
IHC - Paraffin, ELISA


Human FFAR2 / GPR43
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (20 µg/ml)

Specificity and Use

FFAR2 / GPR43 antibody was raised against synthetic 16 amino acid peptide from C-terminus of human GPR43. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (94%).
Human GPR43. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BMI1 (50%).
Immunohistochemistry: LS-A6598 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A6598 was determined to be 14 ug/ml.


PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

Publications (1)

A novel antiinflammatory role for the short-chain fatty acids in human labor. Voltolini C, Battersby S, Etherington SL, Petraglia F, Norman JE, Jabbour HN. Endocrinology. 2012 Jan;153:395-403. [Full Text Article] [PubMed:22186417]

About FFAR2 / GPR43

O15552 NM_005306 NP_005297.1

FFAR2 Antibody, FFA2R Antibody, Free fatty acid receptor 2 Antibody, G protein-coupled receptor 43 Antibody, G-protein coupled receptor 43 Antibody, LSSIG Antibody, GPR43 Antibody, Gpcr43 Antibody

G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules.


Anti-GPR43 antibody LS-A6598 IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: 
Date Requested: 3/19/2018

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