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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FFAR2 / GPR43

free fatty acid receptor 2

G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097). Among SCFAs, the fatty acids containing less than 6 carbons, the most potent activators are probably acetate, propionate and butyrate (PubMed:12496283, PubMed:12711604). Exhibits a SCFA-independent constitutive G protein-coupled receptor activity (PubMed:23066016).

Gene Name: free fatty acid receptor 2
Family/Subfamily: GPCR , Carboxylic Acid
Synonyms: FFAR2, FFA2R, Free fatty acid receptor 2, G protein-coupled receptor 43, G-protein coupled receptor 43, LSSIG, GPR43, Gpcr43
Target Sequences: NM_005306 NP_005297.1 O15552

Viewing 1-25 of 56 items
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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Rabbit Polyclonal to Human FFAR2 / GPR43
Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human FFAR2 / GPR43
Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human FFAR2 / GPR43
Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human FFAR2 / GPR43
Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human FFAR2 / GPR43
Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human FFAR2 / GPR43
Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   0.75mg/ml   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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Rabbit Polyclonal to Human FFAR2 / GPR43
Human
IHC, IHC-P
Unconjugated
50µg   1mg/ml   $425.00
FFAR2 / GPR43 Antibody - Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
ELISA, IHC, IHC-P
Unconjugated
50µg   1mg/ml   $425.00
FFAR2 / GPR43 Antibody - Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
ELISA, IHC, IHC-P
Biotin Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
ELISA, IHC, IHC-P
FITC Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
ELISA, IHC, IHC-P
AP Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
ELISA, IHC, IHC-P
APC Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
ELISA, IHC, IHC-P
PE Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
ELISA, IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human FFAR2 / GPR43
Mouse, Rat, Pig, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
FFAR2 / GPR43 Antibody - Anti-GPR43 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human FFAR2 / GPR43
Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
FFAR2 / GPR43 Antibody - Anti-GPR43 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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Rabbit Polyclonal (IgG) to Human FFAR2 / GPR43
Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50µl   1mg/ml   $425.00
FFAR2 / GPR43 Antibody - Human, Lung, Macrophages: Formalin-Fixed Paraffin-Embedded (FFPE)
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Rabbit Polyclonal to Human FFAR2 / GPR43
Human
IHC, IHC-P, WB
Unconjugated
200µl   $425.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
IHC, IHC-P
FITC Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
IHC, IHC-P
PE Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
IHC, IHC-P
APC Conjugated
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FFAR2 / GPR43
Human
IHC, IHC-P
AP Conjugated
100µl   $650.00

Viewing 1-25 of 56 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).