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Anti-FBXW7 / FBW7 Antibody (Internal) IHC-plus™ LS-B2909

Note: This antibody replaces LS-C14412

Ordering

Wt. Vol. Conc. Price
50 µg - 0.25 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular FBXW7 / FBW7 Antibodies

Anti-FBXW7 / FBW7 Antibody (Internal) IHC-plus™ LS-B2909
Rabbit Polyclonal (IgG) to Human FBXW7 / FBW7
Human
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-FBXW7 / FBW7 Antibody (aa251-300) IHC-plus™ LS-B5634
Rabbit Polyclonal to Mouse FBXW7 / FBW7
Mouse, Rat, Hamster
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-FBXW7 / FBW7 Antibody (clone 3D1) IHC-plus™ LS-B6352
Mouse Monoclonal [clone 3D1] (IgG2a,k) to Human FBXW7 / FBW7
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human FBXW7 / FBW7
Human
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated

Details

Human FBXW7 / FBW7
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (1 - 3 µg/ml)
  • Immunoprecipitation

Specificity and Use

FBXW7 / FBW7 antibody was raised against synthetic peptide derived from an internal region of the human and mouse Cdc4 (archipelago (AGO), F-box/WD-repeat protein 7, F-box and WD-40 domain protein 7, F-box protein FBW7, FBX30 and SEL-10).
Internal
Recognizes human Cdc4 protein at ~60-80kD. Multiple bands may represent various isoforms.
Immunohistochemistry: LS-B2909 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2909 was determined to be 5 ug/ml. Immunoprecipitation: 7 ug/reaction. Positive control: Human T47D, U2-OS, MCF-7, HepG2 and HeLa cell lysates.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About FBXW7 / FBW7

Q969H0 NM_018315 NP_060785.2

FBXW7 Antibody, AGO Antibody, Archipelago homolog Antibody, Archipelago Antibody, CDC4 Antibody, F-box protein FBW7 Antibody, FBXW6 Antibody, F-box protein FBX30 Antibody, F-box protein SEL-10 Antibody, HCdc4 Antibody, Homolog of C elegans sel-10 Antibody, FBW6 Antibody, FBX30 Antibody, FBW7 Antibody, HAgo Antibody, SEL-10 Antibody, SEL10 Antibody

FBXW7 / FBW7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.

Immunohistochemistry

Immunohistochemistry
Anti-FBXW7 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2909 concentration 5 ug/ml.
 

Requested From: United States
Date Requested: 12/3/2016

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