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Anti-EIF2AK2 / PKR Antibody (C-Terminus) LS-C29859

Catalog	Size	Price
LS-C29859-50	50 µg (1 mg/ml)	Unavailable

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Anti-EIF2AK2 / PKR Antibody LS-C497664

Antibody:	Rabbit Monoclonal (IgG) to Human EIF2AK2 / PKR
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Antibody:	Rabbit Polyclonal (IgG) to Human EIF2AK2 / PKR
Reactivity:	Human, Monkey
Application:	IHC - Paraffin, Western blot (applications tested for the base form of this product only)
Format:	Unconjugated

Details

Target:	Human EIF2AK2 / PKR
Host:	Rabbit
Reactivity:	Human, Monkey (tested or 100% immunogen sequence identity)
Clonality:	IgG Polyclonal
Conjugations:	Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

IHC - Paraffin
Western blot (0.13 µg/ml)
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:

EIF2AK2 / PKR antibody was raised against synthetic peptide from C-Terminus of human EIF2AK2 (P19525, NP_002750). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%).

Blocking Peptide:

LS-E10642 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C29859. Useful for pre-absorption and neutralization of the antibody's antigen binding site.

Epitope:

C-Terminus

Specificity:

Human EIF2AK2

Packaging

Presentation:	Lyophilized.
Reconstitution:	50 µl After adding water, will consist of PBS buffer with 2% sucrose
Storage:	Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Restrictions:	For research use only.

About EIF2AK2 / PKR

Uniprot: P19525 NCBI: NM_002759 NP_002750.1

Synonyms: EIF2AK2 Antibody, p1/eIF-2A protein kinase Antibody, p68 kinase Antibody, PRKR Antibody, EIF-2A protein kinase 2 Antibody, p68 Antibody, Protein kinase RNA-activated Antibody, Tik Antibody

Description: IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. Exerts its antiviral activity on a wide range of DNA and RNA viruses including hepatitis C virus (HCV), hepatitis B virus (HBV), measles virus (MV) and herpes simplex virus 1 (HHV-1).

(More About EIF2AK2 / PKR)

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Technical Help Review

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Immunohistochemistry

EIF2AK2 antibody LS-C29859 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Fetal Stomach Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From:
Date Requested: 6/25/2017

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