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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EIF2AK2 / PKR Antibody (C‑Terminus) LS‑C29859
PKR antibody LS-C29859 is an unconjugated rabbit polyclonal antibody to PKR (EIF2AK2) from human and monkey. Validated for IHC and WB.
Catalog
Size
Price
LS-C29859-50
50 µg (1 mg/ml)
Unavailable

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Product Description

PKR antibody LS-C29859 is an unconjugated rabbit polyclonal antibody to PKR (EIF2AK2) from human and monkey. Validated for IHC and WB.
About EIF2AK2 / PKR
IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. Exerts its antiviral activity on a wide range of DNA and RNA viruses including hepatitis C virus (HCV), hepatitis B virus (HBV), measles virus (MV) and herpes simplex virus 1 (HHV-1). P19525 NM_002759 NP_002750.1

EIF2AK2 Antibody, p1/eIF-2A protein kinase Antibody, p68 kinase Antibody, PRKR Antibody, EIF-2A protein kinase 2 Antibody, p68 Antibody, Protein kinase RNA-activated Antibody, Tik Antibody


Specifications

Target
Human EIF2AK2 / PKR
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot (0.13 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
EIF2AK2 / PKR antibody was raised against synthetic peptide from C-Terminus of human EIF2AK2 (P19525, NP_002750). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%).
Blocking Peptide
LS-E10642 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C29859. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
C-Terminus
Specificity
Human EIF2AK2
Presentation
Lyophilized.
Reconstitution
50 µl After adding water, will consist of PBS buffer with 2% sucrose
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

EIF2AK2 antibody LS-C29859 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
EIF2AK2 antibody LS-C29859 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Fetal Stomach Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Stomach Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

EIF2AK2 antibody LS-C29859 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
EIF2AK2 antibody LS-C29859 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Fetal Stomach Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Stomach Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

EIF2AK2 antibody LS-C29859 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
EIF2AK2 antibody LS-C29859 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Fetal Stomach Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Stomach Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

EIF2AK2 antibody LS-C29859 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
EIF2AK2 antibody LS-C29859 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Fetal Stomach Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Stomach Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/23/2018

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