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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EIF2AK2 / PKR Antibody (phospho-Thr451) LS-C17287

PKR antibody LS-C17287 is an unconjugated rabbit polyclonal antibody to human PKR (EIF2AK2). Validated for IHC and WB.
Catalog
Size
Price
LS-C17287-10
10 blot
$635
Description
PKR antibody LS-C17287 is an unconjugated rabbit polyclonal antibody to human PKR (EIF2AK2). Validated for IHC and WB.
Target
Human EIF2AK2 / PKR
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
EIF2AK2 / PKR antibody was raised against synthetic phosphopeptide derived from the region of PKR that contains threonine451. The sequence was aligned to human.
Epitope
pThr451
Specificity
Phosphorylation site-specific antibody selective for the phosphorylated form of the PKR (double-stranded RNA-dependent protein kinase) protein containing a phosphate on threonine451. Recognizes a protein of 65-68kD resolved by SDS-PAGE, identified as PKR. Species cross-reactivity: Human and mouse (73% homologous).
Usage
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:1000. Positive control: HeLa cells stimulated with interferon gamma (IFN ) and calyculin.
Presentation
1 mg/ml BSA (IgG, Protease free), PBS (without Mg2+, Ca2+), pH 7.3, 0.05% Sodium Azide, 50% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About EIF2AK2 / PKR
P19525 NM_002759 NP_002750.1

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Requested From: United States
Date Requested: 4/23/2019
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