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Anti-DRD2 / Dopamine Receptor D2 Antibody (Cytoplasmic Domain) IHC-plus™ LS-A1405

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Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
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DRD2 / Dopamine Receptor D2 Antibody LS-A1405 Images

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Immunohistochemistry
Anti-DRD2 antibody LS-A1405 IHC of human brain, neurons and glia.

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Rabbit Polyclonal to Human DRD2 / Dopamine Receptor D2
Human, Bat, Bovine, Dog, Horse, Rabbit
IHC - Paraffin
Unconjugated

Details

Human DRD2 / Dopamine Receptor D2
Rabbit
Human, Bat, Bovine, Dog, Horse, Rabbit (tested or 100% immunogen sequence identity)
Monkey, Pig (at least 90% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (15 - 20 µg/ml)

Specificity and Use

DRD2 / Dopamine Receptor D2 antibody was raised against synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human DRD2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Ferret, Bat, Bovine, Dog, Elephant, Panda, Horse, Rabbit (100%); Gibbon, Monkey, Pig (94%); Marmoset (81%).
LS-E28264 - Liquid - 50 µg 1 mg/ml - $145.00
Cytoplasmic Domain
Human DRD2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Packaging

PBS, less than 0.1% sodium azide.
Long term: -70°C; Short term: +4°C
For research use only.

About DRD2 / Dopamine Receptor D2

P14416 NM_000795 NP_000786.1

DRD2 Antibody, D2 dopamine receptor Antibody, D2R Antibody, Dopamine receptor D2 isoform Antibody, Dopamine 2 receptor Antibody, D(2) dopamine receptor Antibody, D2DR Antibody, Dopamine D2 receptor Antibody, Dopamine receptor D2 Antibody

The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson's disease. Three alternatively spliced isoforms have been identified.

Immunohistochemistry

Immunohistochemistry
Anti-DRD2 antibody LS-A1405 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: United States
Date Requested: 4/27/2015

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