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DRD2 / Dopamine Receptor D2

dopamine receptor D2

DRD2 / Dopamine Receptor D2 is the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

Gene Name: dopamine receptor D2
Family/Subfamily: GPCR , Dopamine
Synonyms: DRD2, D2R, D(2) dopamine receptor, D2DR
Target Sequences: NM_000795 NP_000786.1 P14416

Publications (2)

1
Dopamine synthesis and dopamine receptor expression are disturbed in recurrent miscarriages. Gratz MJ, Stavrou S, Kuhn C, Hofmann S, Hermelink K, Heidegger H, Hutter S, Mayr D, Mahner S, Jeschke U, Vattai A. Endocrine connections. 2018 May;7:727-738. (Human) [Full Text Article] [PubMed:29686031] [PMC:PMC5958746] Related Antibodies: LS-A1403.
2
Expression of dopaminergic receptors on human CD4+ T lymphocytes: flow cytometric analysis of naive and memory subsets and relevance for the neuroimmunology of neurodegenerative disease. Kustrimovic N, Rasini E, Legnaro M, Marino F, Cosentino M. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2014 Jun;9:302-12. [Full Text Article] [PubMed:24682738] Related Antibodies: LS-C22924.

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Antibodies (35)
Primary (35)
DRD2 / Dopamine Receptor D2 (35)
Human (25)
Mouse (10)
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IHC (4)
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rabbit (35)
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Biotin Conjugated (2)
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HRP Conjugated (2)
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aa194-421 (8)
aa307-336 (7)
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DRD2 / Dopamine Receptor D2 Antibody - Anti-DRD2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
DRD2 / Dopamine Receptor D2 Antibody - Anti-DRD2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Rabbit, Dog, Bovine, Horse, Bat, Human
IHC, IHC-P
Unconjugated
50 µg/$440
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DRD2 / Dopamine Receptor D2 Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Rat, Human
ELISA, WB
Unconjugated
50 µl/$603; 100 µl/$832
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal (3rd Cytoplasmic Domain) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, IP, WB
Unconjugated
50 µg/$941
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DRD2 / Dopamine Receptor D2 Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$832
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$386
DRD2 / Dopamine Receptor D2 Antibody - DRD2 Antibody western blot of mouse NIH-3T3 cell line lysates (35 ug/lane). The DRD2 antibody detected the DRD2 protein (arrow).
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal (aa307-336) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
5 ml/$538
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
5 ml/$538
DRD2 / Dopamine Receptor D2 Antibody - Western blot analysis of extracts of various cell lines, using DRD2 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
100 µl/$587
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
5 ml/$538
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
100 µl/$587
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$717
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, WB
Unconjugated
50 µl/$717
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal (3rd Cytoplasmic Domain) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$801
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal (aa307-336) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal (aa307-336) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal (aa307-336) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal (aa307-336) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal (aa307-336) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal (aa307-336) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
DRD2 / Dopamine Receptor D2 Antibody - Western blot analysis of DRD2 using HT29 whole cells lysates
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DRD2 / Dopamine Receptor D2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).