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DRD2 / Dopamine Receptor D2 is the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.
|Gene Name:||dopamine receptor D2|
|Family/Subfamily:||GPCR , Dopamine|
|Synonyms:||DRD2, D2R, D(2) dopamine receptor, D2DR|
|Target Sequences:||NM_000795 NP_000786.1 P14416|
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