Target
Rat DRD2 / Dopamine Receptor D2
Synonyms
DRD2 | D2R | D(2) dopamine receptor | D2DR
Reactivity
Rat
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated
Immunogen
A 27 AA Peptide (Control peptide) sequence from the rat D2 long form, within the cytoplasmic loop # 3, (2). The 27 AA sequence is unique to the long form and it is not found in the D2 short or other receptor isoform. The peptide was coupled to KLH.
Epitope
3rd Cytoplasmic Domain
Specificity
The 27 AA rat peptide was found only in the D2 long form. No significant sequence homology is seen with other dopamine receptors (D1, D2 short and D3-D5). The 27 AA rat D2RL peptide shows sequence homology of 96% with human/bovine (26/27 AA), 62% with xenopus (17/27 AA) D2L receptors. Antibodies generated to the rat sequence have been shown to recognize the canine D2R. Antibody cross-reactivity with D2L receptors from various species is not known.
Applications
- Western blot (1:500 - 1:2500)
- ELISA (1:5000 - 1:25000)
Usage
Suitable for use in ELISA, Western Blot. Western Blot: 1:500-1:2500. ELISA: 1:5000-1:25000.
Presentation
PBS, 0.05% Sodium Azide, 40% Glycerol
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About DRD2 / Dopamine Receptor D2