Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 202.36] (IgG2b) to Human DPP4 / CD26
Immunoprecipitation, Flow Cytometry
Human DPP4 / CD26
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [202.36]
Specificity and Use
DPP4 / CD26 antibody was raised against a T cell clone. Splenocytes were fused with mouse myeloma NS1 cells.
Reacts with human CD26 (Dipeptidyl peptidase IV), a 110 kD protein which occurs in the cell membrane of T lymphocyte and is upregulated after activation. CD26 is also present on endothelial cells. The mAb was clustered at the VI WLDA.
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion.