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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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DPP4 / CD26

dipeptidyl-peptidase 4

Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

Gene Name: dipeptidyl-peptidase 4
Family/Subfamily: Protease , Serine S9B
Synonyms: DPP4, ADCP-2, ADABP, Dipeptidyl peptidase IV, Dipeptidyl-peptidase 4, DPPIV, ADCP2, T-cell activation antigen CD26, CD26, CD26 antigen, Dipeptidyl peptidase 4, Dipeptidylpeptidase 4, DPP IV, TP103
Target Sequences: NM_001935 NP_001926.2 P27487

Publications (2)

1
Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay. Park JW, Lee JK, Phillips JW, Huang P, Cheng D, Huang J, Witte ON. Proceedings of the National Academy of Sciences of the United States of America. 2016 113:4482-7. (WB; Rat) [Full Text Article] [PubMed:27044116] [PMC:PMC4843433] Related Antibodies: LS-C122983.
2
Overexpression of CD26/DPPIV in mesothelioma tissue and mesothelioma cell lines. Amatya VJ, Takeshima Y, Kushitani K, Yamada T, Morimoto C, Inai K. Oncology reports. 2011 26:1369-75. (IHC-P; Human) [Full Text Article] [PubMed:21894438] Related Antibodies: LS-A8060.


DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
Unconjugated
50µg   1mg/ml   $425.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Rabbit Polyclonal to Human DPP4 / CD26
Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   1mg/ml   $650.00
DPP4 / CD26 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Rabbit, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   0.95mg/ml   $425.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
FITC Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
AP Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
APC Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
PE Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human, Monkey
IHC, IHC-P
Unconjugated
50µg   1mg/ml   $425.00
DPP4 / CD26 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
DPP4 / CD26 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human DPP4 / CD26
Rabbit, Mouse, Rat, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $485.00
DPP4 / CD26 Antibody - Anti-DPP4 / CD26 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Mouse Monoclonal [clone 11D7] (IgG1) to Human DPP4 / CD26
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
FITC Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Anti-CD26 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC, IHC-P
APC Conjugated
100µl   $650.00
DPP4 / CD26 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human DPP4 / CD26
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl   $425.00
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).