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Anti-CXCR2 Antibody (N-Terminus) IHC-plus™ LS-A803

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
Inquire for larger quantities
Same day shipping In Stock - Same day shipping

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Most Popular CXCR2 Antibodies

Anti-CXCR2 Antibody (N-Terminus) IHC-plus™ LS-A802
Rabbit Polyclonal to Human CXCR2
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-CXCR2 Antibody (N-Terminus) IHC-plus™ LS-A803
Rabbit Polyclonal to Human CXCR2
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed In Stock In Stock Publications Publications (1)
Rabbit Polyclonal to Human CXCR2
Human
IHC - Paraffin
Unconjugated

Details

Human CXCR2
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (5 - 10 µg/ml)

Specificity and Use

CXCR2 antibody was raised against synthetic 16 amino acid peptide from N-terminal extracellular domain of human CXCR2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon (100%); Gorilla (94%); Marmoset (88%).
LS-E29313 - Liquid - 50 µg - $145.00
N-Terminus
Human CXCR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Immunohistochemistry: LS-A803 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A803 was determined to be 5 ug/ml.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

Publications (1)

1
Clinical significance of CXCL-8/CXCR-2 network in esophageal squamous cell carcinoma. Ogura M, Takeuchi H, Kawakubo H, Nishi T, Fukuda K, Nakamura R, Takahashi T, Wada N, Saikawa Y, Omori T, Miyasho T, Yamada S, Kitagawa Y. Surgery. 2013 Sep;154:512-20. [Full Text Article] [PubMed:23972657]

About CXCR2

P25025 nm_001557 NP_001548.1

CXCR2 Antibody, CDw128b Antibody, CD182 antigen Antibody, CMKAR2 Antibody, CXCR-2 Antibody, CD182 Antibody, CXC-R2 Antibody, IL-8R B Antibody, Il-8 receptor b Antibody, IL-8 receptor type 2 Antibody, Il-8rb Antibody, IL8R2 Antibody, IL8RB Antibody, Interleukin-8 receptor type B Antibody, GRO/MGSA receptor Antibody, Interleukin 8 receptor beta Antibody, Interleukin 8 receptor, beta Antibody, Chemokine (CXC) receptor 2 Antibody, IL8RA Antibody, Interleukin 8 receptor B Antibody, Interleukin 8 receptor type 2 Antibody

CXCR2 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth.

Immunohistochemistry

Immunohistochemistry
Anti-CXCR2 antibody IHC of human Adrenal, Pheochromocytoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-CXCR2 antibody LS-A803 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-CXCR2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-CXCR2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: United States
Date Requested: 12/2/2016

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