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Anti-CHEK2 / CHK2 Antibody (Ser379) LS-C176402

Catalog Size Price
LS-C176402-100 100 µl Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human CHEK2 / CHK2
Human, Mouse, Rat
IHC, Western blot
Unconjugated

Details

Human CHEK2 / CHK2
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC
  • Western blot

Specificity and Use

CHEK2 / CHK2 antibody was raised against synthetic peptide around Ser379 of human CHK2
Ser379
Human Chk2

Packaging

PBS, pH 7.2, 0.05% sodium azide
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only.

About CHEK2 / CHK2

O96017 NM_007194 NP_009125.1

CHEK2 Antibody, BA444G7 Antibody, Cds1 homolog Antibody, Checkpoint kinase 2 Antibody, Checkpoint-like protein CHK2 Antibody, CHK2 checkpoint homolog Antibody, CHK2 Antibody, HCds1 Antibody, LFS2 Antibody, RAD53 Antibody, Rad53 homolog Antibody, HCHK2 Antibody, HuCds1 Antibody, PP1425 Antibody

Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S/T].

Western blot

Western blot of Chk2 (S379) pAb in extracts from COS7 cells treated with UV 30'.
Western blot of Chk2 (S379) pAb in extracts from COS7 cells treated with UV 30'.

Requested From: 
Date Requested: 4/25/2018

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