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Anti-CDK12 / CRKRS Antibody (clone 3C1) LS-C105145


Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular CDK12 / CRKRS Antibodies

Anti-CDK12 / CRKRS Antibody (Internal) IHC-plus™ LS-A7350
Rabbit Polyclonal to Human CDK12 / CRKRS
Human, Monkey, Dog
IHC - Paraffin
Immunohistochemistry Image
Anti-CDK12 / CRKRS Antibody (C-Terminus) IHC-plus™ LS-A7320
Rabbit Polyclonal to Human CDK12 / CRKRS
Human, Monkey, Mouse, Rat, Bat, Dog, Hamster, Rabbit
IHC - Paraffin
Immunohistochemistry Image
Anti-CDK12 / CRKRS Antibody (clone 3C1) LS-C105145
Mouse Monoclonal [clone 3C1] (IgG2a,k) to Human CDK12 / CRKRS
Western blot, ELISA

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 3C1] (IgG2a,k) to Human CDK12 / CRKRS
Western blot, ELISA


Human CDK12 / CRKRS
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [3C1]
Protein A purified


  • Western blot

  • IHC - Paraffin

Specificity and Use

CDK12 / CRKRS antibody was raised against cRKRS (NP_057591, 1281 a.a. ~ 1380 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.


PBS, pH 7.4.
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.

About CDK12 / CRKRS

Q9NYV4 NM_016507 NP_057591.2

CDK12 Antibody, CDC2-related protein kinase 7 Antibody, CRK7 Antibody, Cyclin-dependent kinase 12 Antibody, HCDK12 Antibody, KIAA0904 Antibody, CRKR Antibody, CRKRS Antibody, Pksc Antibody

Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2.

Requested From: United States
Date Requested: 10/28/2016

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