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Anti-CDK1 / CDC2 Antibody (C-Terminus) LS-C5893

Ordering

Wt. Vol. Conc. Price
200 µg - 0.25 mg/ml $485
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Mouse Monoclonal (IgG2a,k) to Xenopus CDK1 / CDC2
Xenopus, Human, Chicken, Rodent
IHC - Frozen, Western blot, Immunoprecipitation, ELISA, Functional Assay
Unconjugated

Details

Xenopus CDK1 / CDC2
Mouse
Xenopus, Human, Chicken, Rodent (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal
Protein A purified

Applications

IHC - Frozen, Western blot (0.5 - 1 µg/ml), Immunoprecipitation, ELISA (0.1 - 1 µg/ml), Functional Assay

Specificity and Use

CDK1 / CDC2 antibody was raised against recombinant protein consisting of the carboxy-terminal two-thirds of the Xenopus p34cdc2.
C-Terminus
Specific for p34cdc2. Does not appear to cross-react with the related p33cdk2 protein. Inhibits the activation of p34cdc2 kinase by cyclin proteins. Species cross-reactivity: Human, rodent, amphibian and chicken.
Suitable for use in ELISA, Western Blot, Immunoprecipitation, Inhibition and Immunohistochemistry. ELISA: 0.1-1 ug/ml. Western Blot: 0.5-1 ug/ml. Immunoprecipitation: 5 ug. Capable of immunoprecipitating cyclin protein associated with p34cdc2. Inhibition: Inhibits the activation of p34cdc2 kinase by cyclin proteins. Immunohistochemistry (Frozen): 5-10 ug/ml. Positive control: Western Blot: A431 and HeLa 3T3 cell lysates; Xenopus egg extracts.

Packaging

PBS, pH 7.4, 0.1% sodium azide, before the addition of glycerol to 40%
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About CDK1 / CDC2

P06493 NM_001786 NP_001777.1

CDK1 Antibody, CDC28A Antibody, CDC2 Antibody, CDKN1 Antibody, Cyclin-dependent kinase 1 Antibody, p34 protein kinase Antibody, p34CDC2 Antibody, CDC2a Antibody, Cell cycle controller CDC2 Antibody, Cell division protein kinase 1 Antibody, PSTAIR Antibody

Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis.

Requested From: United States
Date Requested: 9/30/2016

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