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Anti-CD53 Antibody (clone MEM-53, Azide-free) LS-C45705


Wt. Vol. Conc. Price
100 µg - - $255
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular CD53 Antibodies

Anti-CD53 Antibody (clone MEM-53) IHC-plus™ LS-B4184
Mouse Monoclonal [clone MEM-53] (IgG1) to Human CD53
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Immunohistochemistry Image

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Mouse Monoclonal [clone MEM-53] (IgG1) to Human CD53
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry, Functional Assay
Unconjugated, Azide-free


Human CD53
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MEM-53]
Protein A purified


  • IHC - Frozen
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry
  • Functional Assay

  • IHC - Paraffin

Specificity and Use

CD53 antibody was raised against leukocytes of patient suffering from a LGL-type leukemia.
Reacts with CD53, a 32-40 kD tetraspanin family glycoprotein exclusively expressed on leukocytes; it is not present on platelets, red blood cells and non-hematopoietic cells. Reacts also with deglycosylated molecule (molecular weight of the antigen is reduced by 15 kD using endoglycosidase F).
Flow Cytometry: Recommended dilution - 4 ug/ml. Immunohistochemistry (frozen sections): It is suitable for discrimination of lymphomas from other tumors. Functional Application: The antibody MEM-53 induces activation of monocytes and B lymphocytes.


Azide free PBS, preserved by filter sterilization, approx., pH 7.4.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About CD53

P19397 NM_000560 NP_000551.1

CD53 Antibody, CD53 antigen Antibody, CD53 molecule Antibody, CD53 tetraspan antigen Antibody, Cell surface antigen Antibody, Leukocyte surface antigen CD53 Antibody, Transmembrane glycoprotein Antibody, Tetraspanin-25 Antibody, Tspan-25 Antibody, CD53 glycoprotein Antibody, Cell surface glycoprotein CD53 Antibody, MOX44 Antibody, TSPAN25 Antibody

CD53 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins.

Requested From: United States
Date Requested: 10/24/2016

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