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Anti-CD46 Antibody (clone MEM-258, FITC) LS-C44290

Note: This antibody replaces LS-C57673


Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $330
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Alternate Forms of this Antibody

LS-B5950 Unconjugated
LS-C44291 RPE Conjugated

Most Popular CD46 Antibodies

Anti-CD46 Antibody (clone 13/42) LS-C96281
Mouse Monoclonal [clone 13/42] (IgG1)
IHC - Paraffin, IHC - Frozen
Immunohistochemistry Image
Anti-CD46 Antibody (clone MEM-258) IHC-plus™ LS-B5950
Mouse Monoclonal [clone MEM-258] (IgG1) to Human CD46
IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone MEM-258] (IgG1) to Human CD46
IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
FITC Conjugated


Human CD46
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MEM-258]
Protein A purified


  • IHC - Paraffin
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:1)
  • (applications tested for the base form of this product only)

Specificity and Use

CD46 antibody was raised against hPB-ALL cell line.
Recognizes the human CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP). CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilization.
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 or 100 ul whole blood. Method sheets are available on request.


PBS, 0.09% sodium azide, 1% BSA.
For research use only.

About CD46

P15529 NM_002389 NP_002380.3

CD46 Antibody, AHUS2 Antibody, CD46 antigen Antibody, MCP Antibody, Measles virus receptor Antibody, TLX Antibody, MIC10 Antibody, TRA2.10 Antibody, Membrane cofactor protein Antibody

Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells.


Anti-CD46 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5950 concentration 10 ug/ml. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.

Requested From: United States
Date Requested: 10/28/2016

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