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Catalog Number Size Price
LS-B5950-0.05 0.05 mg (1 mg/ml) $460 
CD46 Antibody - Anti-CD46 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC‑plus™ Monoclonal Mouse anti‑Human CD46 Antibody (clone MEM‑258, IHC, IF, WB) LS‑B5950

IHC‑plus™ Monoclonal Mouse anti‑Human CD46 Antibody (clone MEM‑258, IHC, IF, WB) LS‑B5950

Note: This antibody replaces LS-C44289, LS-C57675
Antibody:
CD46 Mouse anti-Human Monoclonal (MEM-258) Antibody
Application:
IHC, IHC-P, IF, WB, IP, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-B5950-0.05
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
CD46 Mouse anti-Human Monoclonal (MEM-258) Antibody
Application:
IHC, IHC-P, IF, WB, IP, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
CD46 antibody LS-B5950 is an unconjugated mouse monoclonal antibody to human CD46. Validated for Flow, IF, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Target
Human CD46
Synonyms
CD46 | AHUS2 | CD46 antigen | MCP | Measles virus receptor | TLX | MIC10 | TRA2.10 | Membrane cofactor protein
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
MEM-258
Conjugations
Unconjugated. Also available conjugated with FITC, RPE.
Purification
Protein A purified
Modifications
Unmodified
Immunogen
HPB-ALL cell line.
Specificity
Recognizes the human CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP). CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilization.
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Immunofluorescence
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:10 - 1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 or 100 ul whole blood. Method sheets are available on request.
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD46
P15529 NM_002389 NP_002380.3

Validation

CD46 Antibody - Anti-CD46 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-CD46 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-CD46 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

LSBio Ratings

IHC-plus™ CD46 Antibody (clone MEM-258) for IHC, IF/Immunofluorescence, WB/Western, IP, Flow LS-B5950 has an LSBio Rating of
Laboratory Validation Score (4)

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/13/2024