Human CD46

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

MEM-258

Unconjugated. Also available conjugated with FITC, RPE.

Protein A purified

Unmodified

HPB-ALL cell line.

Recognizes the human CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP). CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilization.

• IHC
• IHC - Paraffin (10 µg/ml)
• Immunofluorescence
• Western blot
• Immunoprecipitation
• Flow Cytometry (1:10 - 1:50)

Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 or 100 ul whole blood. Method sheets are available on request.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P15529 NCBI: NM_002389 NP_002380.3