Target
Dog CD4
Synonyms
CD4 | CD4 antigen | CD4 receptor | CD4mut | CD4 antigen (p55) | CD4 molecule
Reactivity
Dog
(tested or 100% immunogen sequence identity)
Clonality
IgG2a
Monoclonal
Conjugations
R. Phycoerythrin.
Also available
Unconjugated or conjugated with
FITC.
Purification
Protein G purified
Immunogen
Canine Concanavalin A activated T-cell blasts.
Specificity
Is a monoclonal antibody specific for the canine CD4 cell surface antigen. Clone YKIX302.9 was clustered at the first Canine Leukocyte Antigen Workshop (CLAW) [] along with clone CA13.1E4. Has been demonstrated to partially deplete circulating T lymphocytes when administered in vivo, but alone was not sufficient to prolong allograft survival in a canine transplant model. Uniquely amongst mammals, canine CD4 is expressed by neutrophils as well as by lymphocytes subsets. Forms part of a panel of anti canine monoclonal antibodies used extensively in the evaluation of leukemic status in dogs.
Applications
- Flow Cytometry (1:1 - 1:10)
- Applications tested for the base form of this product only
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Reconstitution
Reconstitute with distilled water.
Storage
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee