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Anti-CD135 / FLT3 Antibody (clone BV10A4H2) IHC-plus™ LS-B4049

Note: This antibody replaces LS-C106577
Catalog Size Price
LS-B4049-50 50 µg (0.5 mg/ml) Unavailable

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100% Guaranteed
Mouse Monoclonal [clone BV10A4H2] (IgG1) to Human CD135 / FLT3
Human
IHC - Paraffin, Flow Cytometry
Unconjugated

Details

Human CD135 / FLT3
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [BV10A4H2]
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (20 µg/ml)
  • Flow Cytometry

Specificity and Use

CD135 / FLT3 antibody was raised against human FLT3
The BV10A4H2 antibody has been pre-titrated and tested by flow cytometric analysis of REH cell line. This can be used at 5 ul per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Packaging

PBS, pH 7.2, 150 mM sodium chloride, 0.09% sodium azide
Store at 4°C, avoid repeated freeze thaw cycles.
For research use only.

About CD135 / FLT3

P36888 NM_004119 NP_004110.2

FLT3 Antibody, CD135 Antibody, CD135 antigen Antibody, Fetal liver kinase 2 Antibody, Fetal liver kinase-2 Antibody, FL cytokine receptor Antibody, FLK2 Antibody, FLT-3 Antibody, Fms-like tyrosine kinase 3 Antibody, Stem cell tyrosine kinase 1 Antibody, STK-1 Antibody, FLK-2 Antibody, Fms-related tyrosine kinase 3 Antibody, STK1 Antibody

Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1.

Immunohistochemistry

Immunohistochemistry
Anti-FLT3 / CD135 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4049 concentration 20 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-FLT3 / CD135 antibody IHC of human adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4049 concentration 20 ug/ml.

Requested From: 
Date Requested: 10/18/2017

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