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Anti-CCR3 Antibody (Extracellular Domain) IHC-plus™ LS-A1388

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Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
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Rabbit Polyclonal to Human CCR3
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human CCR3
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (10 µg/ml), ELISA

Specificity and Use

CCR3 antibody was raised against synthetic 16 amino acid peptide from 3rd extracellular domain of human CCR3. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey (88%).
LS-E28257 - Liquid - 50 µg - $145.00
Extracellular Domain
Human CCR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Immunohistochemistry: LS-A1388 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A1388 was determined to be 10 ug/ml.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About CCR3

P51677 NM_001837 NP_001828.1

CCR3 Antibody, C-C chemokine receptor type 3 Antibody, B-chemokine receptor Antibody, CD193 Antibody, CD193 antigen Antibody, Chemokine c-c motif receptor 3 Antibody, C-C chemokine receptor 3 Antibody, CKR3 Antibody, CC-CKR-3 Antibody, CCR-3 Antibody, CMKBR3 Antibody, Eosinophil eotaxin receptor Antibody, Eotaxin receptor Antibody, C-C CKR-3 Antibody, CC chemokine receptor 3 Antibody

CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells.

Immunohistochemistry

Immunohistochemistry
Anti-CCR3 antibody LS-A1388 IHC of human tonsil, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: United States
Date Requested: 9/28/2016

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