Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone ECE.2] (IgG1) to Mouse CCL2 / MCP1
IHC - Paraffin, IHC - Frozen, Western blot
Mouse CCL2 / MCP1
Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [ECE.2]
IHC - Paraffin
IHC - Frozen
Specificity and Use
CCL2 / MCP1 antibody was raised against synthetic peptide corresponding to residues 102-130 of mouse MCP-1
For immunohistology and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
CCL2 / MCP1 is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues.