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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP10 / Caspase 10 Antibody LS‑C192245
Caspase 10 antibody LS-C192245 is an unconjugated rabbit polyclonal antibody to Caspase 10 (CASP10) from human, mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C192245-100
100 µl
Unavailable

Popular CASP10 / Caspase 10 Products

Anti-Caspase 10 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8380 dilution 5 ug/ml.
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Immunohistochemical analysis of Caspase 10 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Product Description

Caspase 10 antibody LS-C192245 is an unconjugated rabbit polyclonal antibody to Caspase 10 (CASP10) from human, mouse and rat. Validated for IHC and WB.
About CASP10 / Caspase 10
CASP10 / Caspase 10 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Q92851 NM_001230 NP_001221.2

CASP10 Antibody, ALPS2 Antibody, Caspase-10 Antibody, Caspase 10 Antibody, CASP-10 Antibody, FADD-like ICE2 Antibody, FLICE2 Antibody, MCH4 Antibody, ICE-like apoptotic protease 4 Antibody, Apoptotic protease Mch-4 Antibody


Specifications

Target
Human CASP10 / Caspase 10
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide from human CASP10 / Caspase 10
Specificity
Human CASP10 / Caspase 10
Presentation
PBS, 0.1% sodium azide, 50% glycerol
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Immunohistochemistry (IHC) analysis of CASP10 pAb in paraffin-embedded Endometrial cancer tissue.
Immunohistochemistry (IHC) analysis of CASP10 pAb in paraffin-embedded Endometrial cancer tissue.

Western blot

Western blot of CASP10 pAb in extracts from Jurkat and NIH3T3 cells.
Western blot of CASP10 pAb in extracts from Jurkat and NIH3T3 cells.

Immunohistochemistry

Immunohistochemistry (IHC) analysis of CASP10 pAb in paraffin-embedded Endometrial cancer tissue.
Immunohistochemistry (IHC) analysis of CASP10 pAb in paraffin-embedded Endometrial cancer tissue.

Western blot

Western blot of CASP10 pAb in extracts from Jurkat and NIH3T3 cells.
Western blot of CASP10 pAb in extracts from Jurkat and NIH3T3 cells.

Immunohistochemistry

Immunohistochemistry (IHC) analysis of CASP10 pAb in paraffin-embedded Endometrial cancer tissue.
Immunohistochemistry (IHC) analysis of CASP10 pAb in paraffin-embedded Endometrial cancer tissue.

Western blot

Western blot of CASP10 pAb in extracts from Jurkat and NIH3T3 cells.
Western blot of CASP10 pAb in extracts from Jurkat and NIH3T3 cells.

Immunohistochemistry

Immunohistochemistry (IHC) analysis of CASP10 pAb in paraffin-embedded Endometrial cancer tissue.
Immunohistochemistry (IHC) analysis of CASP10 pAb in paraffin-embedded Endometrial cancer tissue.

Western blot

Western blot of CASP10 pAb in extracts from Jurkat and NIH3T3 cells.
Western blot of CASP10 pAb in extracts from Jurkat and NIH3T3 cells.


Requested From: 
Date Requested: 6/20/2018

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