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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP10 / Caspase 10

caspase 10, apoptosis-related cysteine peptidase

CASP10 / Caspase 10 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: caspase 10, apoptosis-related cysteine peptidase
Family/Subfamily: Protease , Cysteine C14
Synonyms: CASP10, ALPS2, Caspase-10, Caspase 10, CASP-10, FADD-like ICE2, FLICE2, MCH4, ICE-like apoptotic protease 4, Apoptotic protease Mch-4
Target Sequences: NM_001230 NP_001221.2 Q92851

Filtered by: None
Target
CASP10 / Caspase 10 (62)
Reactivity
Human (60)
Mouse (16)
Rat (7)
Chicken (1)
Chimpanzee (3)
Gibbon (3)
Orangutan (3)
Application
IHC (19)
IHC-Fr (3)
IHC-P (9)
WB (55)
ELISA (17)
ICC (4)
IF (8)
IP (6)
Peptide-ELISA (1)
Host
rabbit (58)
mouse (2)
goat (1)
rat (1)
Isotype
IgG (22)
IgG1,k (1)
IgG2a (1)
IgGa,k (1)
Clonality
monoclonal mc (3)
polyclonal pc (59)
Clone
11J26 (1)
1D8 (1)
4C1 (1)
Format
APC (1)
APC Conjugated (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (46)
Epitope
C-Terminus (8)
aa223-459 (8)
aa281-330 (4)
Internal (2)
N-Terminus (2)
aa505-521 (2)
400-480 aa, C-terminal (1)
Lys442 (1)
aa1-15 (1)
aa1-228 (1)
aa164-192 (1)
aa169-219 (1)
aa206-251 (1)
aa220-236 (1)
aa280-330 (1)
aa430-479 (1)
Publications
No (62)
Showing 1-25 of 62 results

CASP10 / Caspase 10 Antibody (aa430-479) IHC-plus™ LS-B8380
Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10
Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-Caspase 10 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Immunofluorescence analysis of HeLa cells, using Caspase 10 Antibody. The picture on the right is blocked with the synthesized peptide.

CASP10 / Caspase 10 Antibody (C-Terminus) LS-C351929
Rabbit Polyclonal to Human CASP10 / Caspase 10
Mouse, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of Caspase 10 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Caspase 10 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

CASP10 / Caspase 10 Antibody (400-480 aa, C-terminal) LS-C382445
Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10
Human
ELISA IF IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Caspase-10 B/C antibody

CASP10 / Caspase 10 Antibody (C-Terminus) LS-C50302
Rabbit Polyclonal to Human CASP10 / Caspase 10
Human
IHC
Unconjugated
250µl  $575.00
Human liver ca. stained with anti-Caspase 10

CASP10 / Caspase 10 Antibody LS-C261
Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10
Human
ELISA ICC IF WB
Unconjugated
0.1mg 1mg/ml  $365.00
Immunocytochemistry of Casp10 in Hela cells with Caspase 10 antibody at 5 ug/mL.
Immunofluorescence of Casp10 in Hela cells with Caspase 10 antibody at 20 ug/mL.  Green: Caspase-10 Antibody  Blue: DAPI staining

CASP10 / Caspase 10 Antibody LS-C415822
Rabbit Polyclonal to Human CASP10 / Caspase 10
Human
ICC IF IHC WB
Unconjugated
100µg  $305.00
Western blot of HeLa cell lysate using Caspase 10 Antibody

CASP10 / Caspase 10 Antibody LS-C661674
Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10
Human
ELISA IF IHC IP WB
Unconjugated
100µg  $405.00

CASP10 / Caspase 10 Antibody IHC-plus™ LS-B13670
Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10
ELISA IHC IHC-P WB
Unconjugated
40µg 80µl 0.5mg/ml  $425.00
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

CASP10 / Caspase 10 Antibody (Lys442) LS-C175942
Rabbit Polyclonal to Human CASP10 / Caspase 10
Human
IF IHC IHC-P WB
Unconjugated
100µl  $345.00
IHC of Caspase 10 (K442)pAb in paraffin-embedded human lung carcinoma tissue.
Western blot of Caspase 10 (K442) pAb in extracts from HeLa cell.

CASP10 / Caspase 10 Antibody LS-C148253
Rabbit Polyclonal to Human CASP10 / Caspase 10
Human
IHC IHC-Fr IHC-P IP WB
Unconjugated
50µl  $335.00

CASP10 / Caspase 10 Antibody LS-C148252
Rabbit Polyclonal to Human CASP10 / Caspase 10
Human
IHC IHC-Fr IHC-P IP WB
Unconjugated
50µl  $335.00

CASP10 / Caspase 10 Antibody LS-C148254
Rabbit Polyclonal to Human CASP10 / Caspase 10
Human
IHC IHC-Fr IHC-P IP WB
Unconjugated
50µl  $335.00

CASP10 / Caspase 10 Antibody LS-C405392
Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10
Human
ELISA IHC WB
Unconjugated
20µl 0.4mg/ml  $205.00; 60µl 0.4mg/ml  $235.00; 120µl 0.4mg/ml  $295.00; 200µl 0.4mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human brain using CASP10 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of paraffin-embedded Human colon cancer using CASP10 Polyclonal Antibody at dilution of 1:20.

CASP10 / Caspase 10 Antibody (aa220-236) LS-C312671
Rabbit Polyclonal to Human CASP10 / Caspase 10
Human
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $355.00
CASP10 / Caspase 10 antibody. IHC(P): Human Intestinal Cancer Tissue.
Anti-Caspase-10 antibody, IHC(P): Human Intestinal Cancer Tissue

CASP10 / Caspase 10 Antibody LS-C358678
Rabbit Polyclonal to Human CASP10 / Caspase 10
Human
IHC IP WB
Unconjugated
50µl  $325.00

CASP10 / Caspase 10 Antibody LS-C358682
Rabbit Polyclonal to Human CASP10 / Caspase 10
Human
IHC IP WB
Unconjugated
50µl  $325.00

CASP10 / Caspase 10 Antibody LS-C192245
Rabbit Polyclonal to Human CASP10 / Caspase 10
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µl  $385.00
Immunohistochemistry (IHC) analysis of CASP10 pAb in paraffin-embedded Endometrial cancer tissue.
Western blot of CASP10 pAb in extracts from Jurkat and NIH3T3 cells.

CASP10 / Caspase 10 Antibody (C-Terminus) LS-C144568
Rabbit Polyclonal to Human CASP10 / Caspase 10
Human
IHC WB
Unconjugated
100µl  $365.00

CASP10 / Caspase 10 Antibody (C-Terminus) LS-C144569
Rabbit Polyclonal to Human CASP10 / Caspase 10
Human
IHC WB
Unconjugated
25µg  $515.00

CASP10 / Caspase 10 Antibody LS-C403736
Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10
Human
ELISA IHC
Unconjugated
20µl 0.4mg/ml  $205.00; 60µl 0.4mg/ml  $235.00; 120µl 0.4mg/ml  $295.00; 200µl 0.4mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human lung cancer using CASP10 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of paraffin-embedded Human lung cancer using CASP10 Polyclonal Antibody at dilution of 1:30.

CASP10 / Caspase 10 Antibody LS-C330838
Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10
Human
IF WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunofluorescence analysis of U2OS cells using CASP10 antibody. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using CASP10 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.

CASP10 / Caspase 10 Antibody (aa1-228) LS-C182776
Goat Polyclonal (IgG) to Human CASP10 / Caspase 10
Human
ICC WB
Unconjugated
100µg  $770.00

CASP10 / Caspase 10 Antibody (aa1-15) LS-C40710
Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10
Human
ELISA WB
Unconjugated
100µg 100µl 1mg/ml  $275.00

CASP10 / Caspase 10 Antibody (aa169-219) LS-C88895
Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10
Human
ELISA WB
Unconjugated
40µg  $405.00

CASP10 / Caspase 10 Antibody (aa280-330) LS-C88896
Rabbit Polyclonal (IgG) to Human CASP10 / Caspase 10
Human
ELISA WB
Unconjugated
40µg  $405.00
Showing 1-25 of 62 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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