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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BCL2 / Bcl‑2 Antibody (Pro65) LS‑C176387
Bcl-2 antibody LS-C176387 is an unconjugated rabbit polyclonal antibody to Bcl-2 (BCL2) from human, mouse and rat. Validated for IF, IHC and WB.
Catalog
Size
Price
LS-C176387-100
100 µl
Unavailable

Popular BCL2 / Bcl-2 Products

Anti-BCL2 / Bcl-2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1173 concentration 20 ug/ml.
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Formalin-fixed, paraffin-embedded human tonsil stained with peroxidase-conjugate and DAB chromogen. Note absence of staining of reactive cells in the germinal center.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Antibody
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen

Product Description

Bcl-2 antibody LS-C176387 is an unconjugated rabbit polyclonal antibody to Bcl-2 (BCL2) from human, mouse and rat. Validated for IF, IHC and WB.
About BCL2 / Bcl-2
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). P10415 NM_000633 NP_000624.2

BCL2 Antibody, Apoptosis regulator Bcl-2 Antibody, B-cell CLL/lymphoma 2 Antibody, B-cell lymphoma protein 2 Antibody, Bcl-2 Antibody, PPP1R50 Antibody


Specifications

Target
Human BCL2 / Bcl-2
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Immunofluorescence
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
BCL2 / Bcl-2 antibody was raised against synthetic peptide around Pro65 of human Bcl-2
Epitope
Pro65
Specificity
Human Bcl-2
Presentation
PBS, pH 7.2, 15 mM sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of BCL-2 (P65) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of BCL-2 (P65) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of BCL-2 (P65) pAb in extracts from PC12 cells.
Western blot of BCL-2 (P65) pAb in extracts from PC12 cells.

Immunohistochemistry

IHC of BCL-2 (P65) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of BCL-2 (P65) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of BCL-2 (P65) pAb in extracts from PC12 cells.
Western blot of BCL-2 (P65) pAb in extracts from PC12 cells.

Immunohistochemistry

IHC of BCL-2 (P65) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of BCL-2 (P65) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of BCL-2 (P65) pAb in extracts from PC12 cells.
Western blot of BCL-2 (P65) pAb in extracts from PC12 cells.

Immunohistochemistry

IHC of BCL-2 (P65) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of BCL-2 (P65) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of BCL-2 (P65) pAb in extracts from PC12 cells.
Western blot of BCL-2 (P65) pAb in extracts from PC12 cells.


Requested From: 
Date Requested: 6/24/2018

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