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Anti-BCL2 / Bcl-2 Antibody LS-C26455

Catalog	Size	Price
LS-C26455-250	250 µg (1 mg/ml)	Unavailable

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273 BCL2 / Bcl-2 Antibodies

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Anti-BCL2 / Bcl-2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2352 concentration 5 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.

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Formalin-fixed, paraffin-embedded human tonsil stained with peroxidase-conjugate and DAB chromogen. Note absence of staining of reactive cells in the germinal center. This image was taken for the unmodified form of this product. Other forms have not been tested.

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Antibody:	Rabbit Monoclonal (IgG) to Human BCL2 / Bcl-2
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Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

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Reactivity:	Human, Rat, Dog
Application:	Immunofluorescence, Western blot, Immunoprecipitation
Format:	Unconjugated

Details

Target:	BCL2 / Bcl-2
Host:	Sheep
Reactivity:	Human, Rat, Dog (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Modifications:	Unmodified

Applications

Approved:

Immunofluorescence (1:5000)
Western blot
Immunoprecipitation

Specificity and Use

Packaging

Presentation:	PBS, 0.08% Sodium Azide
Restrictions:	For research use only.

About BCL2 / Bcl-2

Uniprot: P10415 NCBI: NM_000633 NP_000624.2

Synonyms: BCL2 Antibody, Apoptosis regulator Bcl-2 Antibody, B-cell CLL/lymphoma 2 Antibody, B-cell lymphoma protein 2 Antibody, Bcl-2 Antibody, PPP1R50 Antibody

Description: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

(More About BCL2 / Bcl-2)

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Date Requested: 4/20/2018

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