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Anti-BCL2 / Bcl-2 Antibody (aa75-110) LS-C98842


Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular BCL2 / Bcl-2 Antibodies

Anti-BCL2 / Bcl-2 Antibody (aa46-95) IHC-plus™ LS-B6548
Rabbit Polyclonal (IgG) to Human BCL2 / Bcl-2
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Immunohistochemistry Image
Anti-BCL2 / Bcl-2 Antibody (C-Terminus) IHC-plus™ LS-B11858
Rabbit Monoclonal (IgG) to Human BCL2 / Bcl-2
Human, Monkey, Mouse, Rat, Bovine
IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal to Human BCL2 / Bcl-2
IHC - Paraffin, ICC, Immunofluorescence, Western blot


Human BCL2 / Bcl-2
Human (tested or 100% immunogen sequence identity)
Ammonium sulfate precipitation


  • IHC - Paraffin (1:10 - 1:50)
  • ICC
  • Immunofluorescence (1:10 - 1:50)
  • Western blot (1:1000)

  • IHC - Paraffin

Specificity and Use

BCL2 / Bcl-2 antibody was raised against kLH-conjugated synthetic peptide between amino acids 75-110 from human Bcl.
LS-E2135 - Lyophilized - 100 µg - $145.00


PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

Publications (1)

Natural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule. Zhao L, He F, Liu H, Zhu Y, Tian W, Gao P, He H, Yue W, Lei X, Ni B, Wang X, Jin H, Hao X, Lin J, Chen Q. The Journal of biological chemistry. 2012 287:1054-65. [PubMed:22065578] [PMC:PMC3256916]

About BCL2 / Bcl-2

P10415 NM_000633 NP_000624.2

BCL2 Antibody, Apoptosis regulator Bcl-2 Antibody, B-cell CLL/lymphoma 2 Antibody, B-cell lymphoma protein 2 Antibody, Bcl-2 Antibody, PPP1R50 Antibody

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).


Formalin-fixed and paraffin-embedded human testis tissue reacted with Bcl-2 BH3 Domain Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.


Confocal immunofluorescence of Bcl-2 Antibody (BH3 Domain Specific) with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Western blot

Western blot
Left panel, of Bcl-2 BH3 domain exposure in HEK293 cells transfected with a plasmid coding for a DNA-binding domain-deleted construct of Nur77 (GFP-Nur77/dDBD) by using this antibody for immunoprecipitation (IP) and a different Bcl-2 antibody for western blot. Right panel, same analysis using antibody in flow cytometry. Data courtesy Dr Quan Chen, Chinese Academy of Sciences.

Requested From: United States
Date Requested: 10/24/2016

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