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Anti-BCL2 / Bcl-2 Antibody (aa67-86) LS-C148230

Catalog Size Price
LS-C148230-50 50 µl Unavailable

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283 BCL2 / Bcl-2 Antibodies

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100% Guaranteed
Rabbit Polyclonal to Mouse BCL2 / Bcl-2
Mouse, Rat
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated

Details

Mouse BCL2 / Bcl-2
Rabbit
Mouse, Rat (tested or 100% immunogen sequence identity)
Hamster, Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Antiserum
Unmodified

Applications

  • IHC
  • IHC - Paraffin (1:1000 - 1:5000)
  • IHC - Frozen
  • Western blot (1:1000 - 1:2000)
  • Immunoprecipitation (1:50 - 1:200)

Specificity and Use

BCL2 / Bcl-2 antibody was raised against a synthetic peptide corresponding to amino acids 67-86 (ARTSPLRPLVATAGPALSPV) of mouse and rat Bcl-2, GenBank no gb/AAP47159.1. This sequence is 100% conserved in mouse and rat Bcl-2 alpha (236 amino acids) and beta (100amino acids) isoforms. Percent identity by BLAST analysis: Mouse, Rat (100%); Hamster, Rabbit (95%); Dog (85%).
aa67-86
Bcl-2.

Packaging

Antiserum, 0.05% sodium azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.

About BCL2 / Bcl-2

P10415 NM_000633 NP_000624.2

BCL2 Antibody, Apoptosis regulator Bcl-2 Antibody, B-cell CLL/lymphoma 2 Antibody, B-cell lymphoma protein 2 Antibody, Bcl-2 Antibody, PPP1R50 Antibody

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Requested From: 
Date Requested: 5/26/2018

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