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Anti-BCL2 / Bcl-2 Antibody (aa41-54) LS-C121403

Catalog Size Price
LS-C121403-100 100 µg Unavailable

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100% Guaranteed
Mouse Monoclonal (IgG1) to Human BCL2 / Bcl-2
Human
IHC, IHC - Paraffin, IHC - Frozen, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated

Details

Human BCL2 / Bcl-2
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC
  • IHC - Paraffin (0.4 - 1 µg/ml)
  • IHC - Frozen (0.4 - 1 µg/ml)
  • ICC
  • Immunofluorescence
  • Western blot (1 - 2 µg/ml)
  • Immunoprecipitation

Specificity and Use

BCL2 / Bcl-2 antibody was raised against synthetic peptide corresponding to residues 41-54 of the bcl-2 protein, conjugated to thyroglobulin.
aa41-54
Recognizes human Bcl-2.
Suitable for use in Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry, and Immunofluorescence. Western Blot: 1-2 ug/ml. Immunohistochemistry (paraffin, frozen): 0.4-1 ug/ml.

Packaging

Lyophilized from 1.2% sodium acetate, 2 mg BSA, 0.01 mg sodium azide
Sterile distilled water
Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.
For research use only.

About BCL2 / Bcl-2

P10415 NM_000633 NP_000624.2

BCL2 Antibody, Apoptosis regulator Bcl-2 Antibody, B-cell CLL/lymphoma 2 Antibody, B-cell lymphoma protein 2 Antibody, Bcl-2 Antibody, PPP1R50 Antibody

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Requested From: 
Date Requested: 5/26/2018

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