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Human BAX | |
Mouse | |
Human, Mouse, Rat (tested or 100% immunogen sequence identity) | |
IgG1 Monoclonal | |
Unconjugated | |
Purified | |
Unmodified |
BAX antibody was raised against kLH-conjugated peptide corresponding to amino acids 12-24 located near the N-terminus common to human, mouse and rat Bax. | |
N-Terminus | |
Recognizes human Bax (Mr 20-22kD). Species cross-reactivity: Mouse and rat. | |
Immunoprecipitation. Immunofluorescence staining. Western Blot. Enzyme-Linked-Immunosorbent-Assay (ELISA). Western Blot: 1 ug/ml. |
100 mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added. | |
Short term: +4°C; Long term: Add glycerol (40-50%) -20°C. | |
For research use only. |
BAX Antibody, BCL2-associated X protein Antibody, Bcl2-L-4 Antibody, Apoptosis regulator BAX Antibody, Bcl-2-like protein 4 Antibody, BCL2L4 Antibody
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.